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A case of anti-Js(b) in pregnancy was associated with unexpectedly severe haemolytic disease of the newborn, requiring urgent exchange transfusion. Clinical signs of fetal distress were evident at 35 weeks of gestation in a sixth pregnancy. A Js(b+) baby from a previous pregnancy had been unaffected. This case report illustrates the difficulties of predicting severity on the basis of anti-Js(b) titre, and highlights issues relating to the problems of using reconstituted frozen red cells from the rare red cell bank for exchange transfusion.

Original publication




Journal article


Vox Sang

Publication Date





134 - 135


Adult, Erythroblastosis, Fetal, Erythropoietin, Exchange Transfusion, Whole Blood, Female, Humans, Infant, Newborn, Kell Blood-Group System, Pregnancy, Pregnancy Complications, Recombinant Proteins