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A case of anti-Js(b) in pregnancy was associated with unexpectedly severe haemolytic disease of the newborn, requiring urgent exchange transfusion. Clinical signs of fetal distress were evident at 35 weeks of gestation in a sixth pregnancy. A Js(b+) baby from a previous pregnancy had been unaffected. This case report illustrates the difficulties of predicting severity on the basis of anti-Js(b) titre, and highlights issues relating to the problems of using reconstituted frozen red cells from the rare red cell bank for exchange transfusion.

Original publication

DOI

10.1046/j.1423-0410.2001.00092.x

Type

Journal article

Journal

Vox Sang

Publication Date

2001

Volume

81

Pages

134 - 135

Keywords

Adult, Erythroblastosis, Fetal, Erythropoietin, Exchange Transfusion, Whole Blood, Female, Humans, Infant, Newborn, Kell Blood-Group System, Pregnancy, Pregnancy Complications, Recombinant Proteins