Genetic polymorphism A1675G of the angiotensin type 2 receptor and its role in hypertension
Koumallos N., Tousoulis D., Antoniades C., Antonopoulos AS., Stefanadis C.
The angiotensin type 2 receptor (AT2R) plays a crucial role in the regulation of blood pressure and atherogenesis. The AT2R gene is located on chromosome X and the biological effect of polymorphism A1675G in this gene still needs to be further specified. This is a review of all the studies examining the role of A1675G in arterial hypertension and cardiac disease. © Athens Medical Society.