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Muscle LIM Protein (MLP) is small, just 198 amino acid long protein, which is specifically expressed in slow skeletal muscle and cardiac tissues. This article will focus on the cardiac functions of MLP: the current knowledge about localisation data, binding partners and animal models for the protein will be summarised, and the role of MLP in maintaining a healthy heart be discussed. This review will furthermore attempt to identify gaps in our knowledge-and hence future research potential-with a special focus on MLP's role in cardiac mechano-signalling.

Original publication

DOI

10.1007/s10974-008-9159-4

Type

Journal article

Journal

J Muscle Res Cell Motil

Publication Date

2008

Volume

29

Pages

155 - 158

Keywords

Animals, Humans, LIM Domain Proteins, Muscle Proteins, Muscle, Skeletal, Myocardial Contraction, Myocardium