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The recent development of transposon and CRISPR-Cas9-based tools for manipulating the fly genome in vivo promises tremendous progress in our ability to study developmental processes. Tools for introducing tags into genes at their endogenous genomic loci facilitate imaging or biochemistry approaches at the cellular or subcellular levels. Similarly, the ability to make specific alterations to the genome sequence allows much more precise genetic control to address questions of gene function.

Original publication

DOI

10.3390/jdb5040016

Type

Journal article

Journal

Journal of Developmental Biology

Publisher

MDPI AG

Publication Date

11/12/2017

Volume

5

Pages

16 - 16