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Depth of response is the critical determinant of prognosis in amyloid light-chain (AL) amyloidosis. Here, we aim to identify patients who are unlikely to improve response based on analysis of baseline characteristics and 1-month response. In a multivariate model, difference in involved amyloidogenic and uninvolved serum free light chains (dFLC) at diagnosis (dFLC >400 mg/l, odds ratio [OR] 4.051, p 400 mg/l and no response at 1 month improved their response (p 

Original publication




Journal article


Br J Haematol

Publication Date



MGUS, amyloidosis, multiple myeloma