Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Optimal glycemic control in kidney transplant recipients with diabetes is associated with improved morbidity and better patient and allograft survival. Transplant options for patients with diabetes requiring insulin therapy and chronic kidney disease who are suitable candidates for kidney transplantation should include consideration of β-cell replacement therapy: pancreas or islet transplantation. International variation related to national regulatory policies exists in offering one or both options to suitable candidates and is further affected by pancreas/islet allocation policies and transplant waiting list dynamics. The selection of appropriate candidates depends on patient age, coexistent morbidities, the timing of referral to the transplant center (predialysis versus on dialysis) and availability of living kidney donors. Therefore, early referral (estimated glomerular filtration rate

Original publication

DOI

10.1053/j.ajkd.2021.02.339

Type

Journal article

Journal

Am J Kidney Dis

Publication Date

09/2021

Volume

78

Pages

418 - 428

Keywords

chronic kidney disease (CKD), diabetes mellitus, hypoglycemia unawareness, kidney transplantation, pancreas after kidney transplantation (PAK), review, simultaneous islet-kidney transplantation (SIK), simultaneous pancreas-kidney transplantation (SPK), β-cell replacement therapy, Diabetes Mellitus, Type 1, Global Health, Graft Survival, Humans, Kidney Diseases, Kidney Transplantation, Living Donors, Morbidity, Postoperative Complications, Transplantation, Homologous