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Percutaneous mechanical closure of the left atrial appendage (LAA) is a valuable stroke prevention strategy in patients with atrial fibrillation and contraindication to oral anticoagulation. LAA thrombus is a common finding in patients with atrial fibrillation and frequently fails to resolve despite therapeutic anticoagulation. In this scenario, LAA occlusion device implant is generally discouraged due to the high risk of thrombus dislodgement and embolization; however, alternative management options are limited. We report the first case of a successful LAA occlusion device (Watchman-FLX) implant in the presence of a proximal thrombus.

Original publication




Journal article


J Cardiovasc Electrophysiol

Publication Date





1655 - 1657


Watchman-FLX, left atrial appendage occlusion, proximal thrombus, stroke prevention, Atrial Appendage, Atrial Fibrillation, Heart Diseases, Humans, Stroke, Thrombosis