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A 63-year-old woman was diagnosed with acute myelo-monocytic leukaemia, associated with MLL gene rearrangement, 16 months after completion of oral capecitabine for metastatic colon cancer. Capecitabine, recommended for use in metastatic breast and colon cancer and more recently as adjuvant treatment of colon cancer, has not previously been reported to be associated with secondary cancer.

Original publication

DOI

10.1111/j.1600-0609.2007.00864.x

Type

Journal article

Journal

Eur J Haematol

Publication Date

06/2007

Volume

78

Pages

543 - 544

Keywords

Acute Disease, Antimetabolites, Antineoplastic, Capecitabine, Colorectal Neoplasms, Deoxycytidine, Fluorouracil, Humans, Leukemia, Myeloid