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Angioedema is a recognised side effect of rofecoxib, a cyclo-oxygenase-2 (COX-2) inhibitor. But death resulting from a haemorrhagic pulmonary oedema after its ingestion has not been recorded. The case of a 60 year old man who died from haemorrhagic pulmonary oedema in the presence of angioedema after the ingestion of two doses of 12.5 mg of rofecoxib is reported.

Original publication

DOI

10.1136/pmj.78.921.439

Type

Journal article

Journal

Postgrad Med J

Publication Date

07/2002

Volume

78

Pages

439 - 440

Keywords

Angioedema, Anti-Inflammatory Agents, Non-Steroidal, Cyclooxygenase Inhibitors, Fatal Outcome, Hemorrhage, Humans, Lactones, Lung Diseases, Male, Middle Aged, Pulmonary Edema, Sulfones