Oxford Centre for Diabetes, Endocrinology and Metabolism
A pioneering centre combining clinical care, research and education in diabetes, endocrine and metabolic diseases
About OCDEM
OCDEM is one of the leading research centres in diabetes, endocrinology and metabolism in the UK.
Our People
Discover our directory of staff and students working and studying in OCDEM.
Public Engagement
Find out how we ensure our research reaches patients and the public.
Find us
Contact information, a map and transport information for visiting OCDEM.
Latest news
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Scientists reveal how new diabetes and obesity drugs work
19 August 2025
Research capacity
The Oxford BioBank
The Oxford BioBank is a resource for medical research to translate early discoveries into benefit for patients.
Advanced Imaging Suite
The suite comprises live imaging, confocal, super-resolution and single-molecule capability.
Human Islet Isolation Facility
Here we isolate high quality human islets for both clinical and research use.
GS-MS Metabolic Tracing
The mass-spectrometry suite is predominantly used for stable-isotope analysis in cells, blood and tissues.
Research Groups
Hodson Group: Cellular Metabolism and GPCR Signalling
Investigating how cellular metabolism and GPCR signalling converge to influence energy homeostasis in the periphery and brain during health and metabolic disease.
Karpe, Hodson and Christodoulides Group: Metabolic Research Group
Applying an integrated approach to human metabolic disease which involves genetic, genomic, cell biology and whole body metabolic studies to understand the pathogenesis of the complications of obesity.
Ray Group
Working on circadian rhythms, and nuclear receptors applied to both inflammation and energy metabolism.
Rorsman Group
Studying cellular physiology of pancreatic islets - the small organs that regulate the whole-body sugar levels.
Thakker Group: Academic Endocrine Unit
Investigating the genetic, molecular and physiological basis of endocrine disorders that affect calcium homeostasis, and endocrine tumour development.
Tomlinson Group: Metabolism and Steroid Hormone Biology
Understanding how hormones regulate metabolic health in liver, fat and skeletal muscle.
Nasteska Group: Islet Protein Turnover
Exploring protein synthesis dynamics in pancreatic islets over time and across beta cell population, searching for subpopulations with differential synthesis.
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The Oxford Stone Group
Learning more about kidney stone disease and how best to prevent, diagnose and treat this condition.