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Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of activated platelets than P-selectin during thrombus formation in vivo.

Original publication

DOI

10.1182/bloodadvances.2018017756

Type

Journal article

Journal

Blood Adv

Publication Date

28/08/2018

Volume

2

Pages

2072 - 2078

Keywords

Animals, Biomarkers, Blood Platelets, Humans, Mice, P-Selectin, Platelet Activation, Receptors, Immunologic