Publications — Radcliffe Department of Medicine

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Single cell analysis of bone marrow derived CD34+ cells from children with sickle cell disease and thalassemia

Hua P. et al, (2019), Blood

Identification of two distinct pathways of human myelopoiesis.

Drissen R. et al, (2019), Sci Immunol, 4

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.

Rodriguez-Meira A. et al, (2019), Mol Cell, 73, 1292 - 1305.e8

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Chagraoui H. et al, (2018), Nat Commun, 9

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo.

Lukoseviciute M. et al, (2018), Dev Cell, 47, 608 - 628.e6

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Mead AJ. et al, (2017), J Exp Med, 214, 2005 - 2021

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A. et al, (2017), Nat Med, 23, 692 - 702

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC. et al, (2016), Nat Immunol, 17, 1424 - 1435

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R. et al, (2016), Nat Immunol, 17, 666 - 676

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Grover A. et al, (2016), Nat Commun, 7

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

Buono M. et al, (2016), Nat Cell Biol, 18, 157 - 167

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

Stadhouders R. et al, (2015), Nat Commun, 6

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo

Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.

Stadhouders R. et al, (2014), J Clin Invest, 124, 1699 - 1710

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Sanjuan-Pla A. et al, (2013), Nature, 502, 232 - 236

Locus-specific proteomics by TChP: targeted chromatin purification.

Pourfarzad F. et al, (2013), Cell Rep, 4, 589 - 600

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

Sanjuan-Pla A. et al, (2013), Nature, 502, 232 - 236

r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data.

Thongjuea S. et al, (2013), Nucleic Acids Res, 41

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