Publications — Radcliffe Department of Medicine

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Functional annotation of human long noncoding RNAs via molecular phenotyping

Ramilowski JA. et al, (2020), Genome Research, 30, 1060 - 1072

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.

Psaila B. et al, (2020), Mol Cell, 78, 477 - 492.e8

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.

Di Genua C. et al, (2020), Cancer Cell

The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission.

Jeanpierre S. et al, (2020), Haematologica

Technological advances and computational approaches for alternative splicing analysis in single cells.

Wen WX. et al, (2020), Comput Struct Biotechnol J, 18, 332 - 343

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.

Hua P. et al, (2019), Blood, 134, 2111 - 2115

Identification of two distinct pathways of human myelopoiesis.

Drissen R. et al, (2019), Sci Immunol, 4

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.

Rodriguez-Meira A. et al, (2019), Mol Cell, 73, 1292 - 1305.e8

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Chagraoui H. et al, (2018), Nat Commun, 9

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo.

Lukoseviciute M. et al, (2018), Dev Cell, 47, 608 - 628.e6

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Mead AJ. et al, (2017), J Exp Med, 214, 2005 - 2021

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A. et al, (2017), Nat Med, 23, 692 - 702

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC. et al, (2016), Nat Immunol, 17, 1424 - 1435

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R. et al, (2016), Nat Immunol, 17, 666 - 676

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Grover A. et al, (2016), Nat Commun, 7

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

Buono M. et al, (2016), Nat Cell Biol, 18, 157 - 167

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

Stadhouders R. et al, (2015), Nat Commun, 6

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo

Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS. et al, (2014), Cancer Cell, 25, 794 - 808

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