Publications — Radcliffe Department of Medicine

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Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S. et al, (2017), Nat Commun, 8

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A. et al, (2017), Nat Med, 23, 692 - 702

Subset-Specific Expression of Toll-Like Receptors by Bovine Afferent Lymph Dendritic Cells.

Werling D. et al, (2017), Front Vet Sci, 4

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

Handel AE. et al, (2016), Hum Mol Genet, 25, 989 - 1000

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Giustacchini A. et al, (2015), BLOOD, 126

Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin

Hope JC. et al, (2012), Vaccine, 30, 2357 - 2367

Production and characterization of two monoclonal antibodies to bovine tumour necrosis factor alpha (TNF-alpha) and their cross-reactivity with ovine TNF-alpha.

Kwong LS. et al, (2010), Vet Immunol Immunopathol, 135, 320 - 324

Natural killer cell number and phenotype in bovine peripheral blood is influenced by age.

Graham EM. et al, (2009), Vet Immunol Immunopathol, 132, 101 - 108

A toolbox facilitating stable transfection of Eimeria species.

Clark JD. et al, (2008), Mol Biochem Parasitol, 162, 77 - 86

Development of a simple, sensitive, rapid test which discriminates BCG-vaccinated from Mycobacterium bovis-infected cattle.

Sopp P. et al, (2008), Vaccine, 26, 5470 - 5476

Cross-reactivity of mAbs to human CD antigens with cells from cattle.

Sopp P. et al, (2007), Vet Immunol Immunopathol, 119, 106 - 114

Workshop cluster 1+ gammadelta T-cell receptor T cells from calves express high levels of interferon-gamma in response to stimulation with interleukin-12 and -18.

Price SJ. et al, (2007), Immunology, 120, 57 - 65

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle.

Sopp P. et al, (2006), Clin Vaccine Immunol, 13, 1343 - 1348

Subsets of afferent lymph dendritic cells differ in their capacity to phagocytose Mycobacterium bovis

Hope JC. et al, (2005), IMMUNOLOGY, 116, 21 - 21

Summary of the animal homologue section of HLDA8.

Saalmüller A. et al, (2005), Cell Immunol, 236, 51 - 58

Development of detection methods for ruminant interleukin (IL)-4.

Hope JC. et al, (2005), J Immunol Methods, 301, 114 - 123

The role of dendritic cells in shaping the immune response.

Howard CJ. et al, (2004), Anim Health Res Rev, 5, 191 - 195

Phenotypic and functional characterization of intraepithelial lymphocytes in a bovine ligated intestinal loop model of enterohaemorrhagic Escherichia coli infection.

Menge C. et al, (2004), J Med Microbiol, 53, 573 - 579

Exposure to Mycobacterium avium primes the immune system of calves for vaccination with Mycobacterium bovis BCG.

Howard CJ. et al, (2002), Clin Exp Immunol, 130, 190 - 195

Development of detection methods for ruminant interleukin (IL)-12.

Hope JC. et al, (2002), J Immunol Methods, 266, 117 - 126

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