Publications — Radcliffe Department of Medicine

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Pan-cancer Genome Analysis: In the Clouds?

Orlando G. and Mead A., (2020), The Hematologist, 17

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

Speedy HE. et al, (2019), Nature Communications, 10

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes

Went M. et al, (2019), Human Genomics, 13

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Law PJ. et al, (2019), Nat Commun, 10

Identification of recurrent noncoding mutations in B-cell lymphoma using capture Hi-C

Cornish AJ. et al, (2019), Blood Advances, 3, 21 - 32

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

Went M. et al, (2019), Blood Cancer Journal, 9

Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma

Sud A. et al, (2018), Blood, 132, 2040 - 2052

Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer

Orlando G. et al, (2018), Nature Genetics, 50, 1375 - 1380

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Went M. et al, (2018), Nat Commun, 9

Capture Hi-C Library Generation and Analysis to Detect Chromatin Interactions

Orlando G. et al, (2018), Current Protocols in Human Genetics, 98, e63 - e63

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci.

Tanskanen T. et al, (2018), Int J Cancer, 142, 540 - 546

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.

Sud A. et al, (2017), Nat Commun, 8

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

Li N. et al, (2017), Cell Reports, 20, 2556 - 2564

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.

Litchfield K. et al, (2017), Nat Genet, 49, 1133 - 1140

Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci

Law PJ. et al, (2017), Scientific Reports, 7

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression

Li N. et al, (2016), Nature Communications, 7

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.

Orlando G. et al, (2016), Hum Mol Genet, 25, 2349 - 2359

WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation

Pfister SX. et al, (2016), CANCER RESEARCH, 76

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation.

Pfister SX. et al, (2015), Cancer Cell, 28, 557 - 568

ARF induction in response to DNA strand breaks is regulated by PARP1.

Orlando G. et al, (2014), Nucleic Acids Res, 42, 2320 - 2329

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