Publications — Radcliffe Department of Medicine

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The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1.

Stanly TA. et al, (2020), J Biol Chem, 295, 5036 - 5050

Distinct requirements for tissue-resident myeloid lineages during cardiac lymphatic development

JACKSON D. et al, (2020), eLife, Submitted

TNF-derived peptides inhibit tumour growth and metastasis through cytolytic effects on tumour lymphatics.

Lu W. et al, (2019), Clin Exp Immunol

Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.

Jackson DG., (2019), Matrix Biol, 78-79, 219 - 235

Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.

Sun M. et al, (2019), Invest Ophthalmol Vis Sci, 60, 1050 - 1062

Leucocyte Trafficking via the Lymphatic Vasculature- Mechanisms and Consequences.

Jackson DG., (2019), Front Immunol, 10

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim HY. et al, (2018), Immunity, 49, 326 - 341.e7

The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction.

Vieira JM. et al, (2018), J Clin Invest, 128, 3402 - 3412

Lymphatic exosomes promote dendritic cell migration along guidance cues.

Brown M. et al, (2018), J Cell Biol, 217, 2205 - 2221

TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides.

Bauer J. et al, (2018), J Mol Med (Berl), 96, 199 - 209

Developmental Programming of the Cardiac Lymphatics towards improved Heart Repair

Norman S. et al, (2017), HUMAN GENE THERAPY, 28, A5 - A5

Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1.

Johnson LA. et al, (2017), Nat Immunol, 18, 762 - 770

The role of the actin cytoskeleton in regulating receptor dynamics and function

Stanly TA. et al, (2017), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 46, S378 - S378

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium.

Banerji S. et al, (2016), J Biol Chem, 291, 25004 - 25018

Lymphatic Regulation of Cellular Trafficking

Jackson DG., (2016), J Clin Cell Immunol

Homodimerisation of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-Labile Disulfide is critical for Hyaluronan Binding in Lymphatic Endothelium.

Jackson DG. et al, (2016), Journal of Biological Chemistry

A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force.

Bano F. et al, (2016), Sci Rep, 6

Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters.

Stanly TA. et al, (2016), Biol Open, 5, 1343 - 1350

Micromechanical Analysis of the Hyaluronan-Rich Matrix Surrounding the Oocyte Reveals a Uniquely Soft and Elastic Composition.

Chen X. et al, (2016), Biophys J, 110, 2779 - 2789

Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization.

Lawrance W. et al, (2016), J Biol Chem, 291, 8014 - 8030

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