Publications — Radcliffe Department of Medicine

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Specification of the haematopoietic stem cell lineage: From blood-fated mesodermal angioblasts to haemogenic endothelium.

Ho VW. et al, (2022), Semin Cell Dev Biol

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Juban G. et al, (2021), Haematologica, 106, 1106 - 1119

Publisher Correction: The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors.

Harland LTG. et al, (2021), Nat Cell Biol

The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors.

Harland LTG. et al, (2021), Nat Cell Biol, 23, 61 - 74

EOMESODERMIN GOVERNS THE HEMOGENIC COMPETENCE OF MURINE YOLK-SAC MESODERMAL PROGENITORS

Harland L. et al, (2020), EXPERIMENTAL HEMATOLOGY, 88, S34 - S34

H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domai

PORCHER C. et al, (2020), Royal Society Open Science

The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain.

Karia D. et al, (2020), R Soc Open Sci, 7

Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos.

Li L. et al, (2019), Nat Commun, 10

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Chagraoui H. et al, (2018), Nat Commun, 9

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells.

Karamitros D. et al, (2018), Nat Immunol, 19, 85 - 97

SCL/TAL1: a multifaceted regulator from blood development to disease.

Porcher C. et al, (2017), Blood, 129, 2051 - 2060

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

Quek L. et al, (2016), J Exp Med, 213, 1513 - 1535

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.

Chen I-I. et al, (2016), Sci Rep, 6

An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference.

Blobel GA. et al, (2015), Exp Hematol, 43, 821 - 837

Toward a BETter grasp of acetyl-lysine readers.

Porcher C., (2015), Blood, 125, 2739 - 2741

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34-Human Acute Myeloid Leukemia

Quek L. et al, (2014), BLOOD, 124

Structural Basis for LMO2-Driven Recruitment of the SCL: E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets

ElOmari K. et al, (2013), Cell Reports, 4, 135 - 147

Structural basis for LMO2-driven recruitment of the SCL:E47bHLH heterodimer to hematopoietic-specific transcriptional targets.

El Omari K. et al, (2013), Cell Rep, 4, 135 - 147

GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis.

Papadopoulos GL. et al, (2013), Nucleic Acids Res, 41, 4938 - 4948

Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

Leung A. et al, (2013), Developmental Cell, 24, 144 - 158

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