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Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.

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Hertzog J. et al, (2022), EMBO J, 41

Interferon induction held captive in tumor cells.

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Bridgeman A. and Rehwinkel J., (2021), Mol Cell, 81, 4109 - 4110

Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.

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Chauveau L. et al, (2021), EMBO Rep, 22

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.

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Clapes T. et al, (2021), Nat Cell Biol, 23, 704 - 717

The RNA sensor MDA5 detects SARS-CoV-2 infection.

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Sampaio NG. et al, (2021), Sci Rep, 11

cGAMP loading enhances the immunogenicity of VLP vaccines

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Chauveau L. et al, (2020)

Deoxyguanosine is a TLR7 agonist.

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Davenne T. et al, (2020), Eur J Immunol, 50, 56 - 62

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

Journal article

Glück S. et al, (2017), Nat Cell Biol, 19, 1061 - 1070

Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.

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Maelfait J. et al, (2017), EMBO J, 36, 2529 - 2543

Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture.

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Mayer A. et al, (2017), Methods Mol Biol, 1656, 143 - 152

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.

Journal article

Maelfait J. et al, (2016), Cell Rep, 16, 1492 - 1501

Viruses transfer the antiviral second messenger cGAMP between cells.

Journal article

Bridgeman A. et al, (2015), Science, 349, 1228 - 1232

Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice.

Journal article

Ondondo B. et al, (2014), Clin Vaccine Immunol, 21, 1565 - 1572

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

Journal article

Borthwick N. et al, (2014), Mol Ther, 22, 464 - 475

SAMHD1-dependent retroviral control and escape in mice.

Journal article

Rehwinkel J. et al, (2013), EMBO J, 32, 2454 - 2462

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