Backtracking to the future: unraveling the origins of childhood leukemia.
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Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.
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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
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The management of myelofibrosis: A British Society for Haematology Guideline.
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Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis.
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Fang Z. et al, (2023), Nat Commun, 14
Outcomes and Characteristics of Non-Melanoma Skin Cancers in Patients with Myeloproliferative Neoplasms on Ruxolitinib.
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Rampotas A. et al, (2023), Blood
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.
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Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632
Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline.
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McLornan DP. et al, (2023), Br J Haematol
Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts.
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Moura PL. et al, (2023), Cancer Res
Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study.
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Mesa RA. et al, (2023), Hemasphere, 7
RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort.
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O'Sullivan JM. et al, (2023), Leukemia
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
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Luis TC. et al, (2023), Nat Commun, 14
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.
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Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells
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Long-term treatment with pacritinib on a compassionate use basis in patients with advanced myelofibrosis.
Conference paper
Harrison C. et al, (2023), Haematologica, 108, 1960 - 1964
Ruxolitinib Versus Best Available Therapy for Polycythemia Vera Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial.
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Harrison CN. et al, (2023), J Clin Oncol
Symptomatic benefit of momelotinib in patients with myelofibrosis: Results from the SIMPLIFY phase III studies.
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Quantifying inherent predictability and spatial synchrony in the aphid vector Myzus persicae: field-scale patterns of abundance and regional forecasting error in the UK.
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MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data.
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Wen WX. et al, (2023), Nucleic Acids Res, 51
MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis.
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Mascarenhas J. et al, (2023), J Clin Oncol