BSc (Hons.) MPhil (Cantab.) AMRSB
- Radcliffe Department of Medicine Scholar
- Clarendon Fund and Mary Somerville Graduate Scholar
Clinical Genetics of Craniosynostosis
Supervised by Prof. Andrew Wilkie and Dr. Stephen Twigg, my work focuses on craniosynostosis, the premature fusion of one or more sutures separating the bones of the skull vault. A complex network of developmental mechanisms is involved in patterning and maintaining this complex system of bones, and a variety of genetic mutations can affect these processes to cause serious skull malformations. Oxford is a leading national referral centre in the surgical treatment of these cranial malformations, enabling us to study the entire process by which these arise from patient to mutation, and from mouse models to molecular pathogenesis.