Contact information
philip.langer@cardiov.ox.ac.uk
https://orcid.org/0009-0007-2648-9739
Division of Cardiovascular Medicine, Level 6 West Wing, John Radcliffe Hospital, University of Oxford, OX3 0AG
Recent Biography
Since completing my PhD, I have joined Prof Robin Choudhury's Group here at the RDM, as part of the wider MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT).
We are focused on creating novel immunomodulatory gene therapies to combat fibrosis post-myocardial infarction to create the optimal environment for myocardial regeneration.
During my BSc (Hons) Pharmacology with a Modern Language degree at the University of Manchester and Nagoya University, I developed a strong interest in the delivery of biopharmaceuticals via gene therapy.
Further expanding on this interest, I subsequently completed a PhD at the University of Bristol and University of Washington, within the Ophthalmology Research Group led by Prof Andrew Dick as part of the NIHR Moorfields BRC.
My doctoral research focused on characterising, manipulating, and overcoming the retinal immune response to recombinant adeno-associated virus (rAAV) vectors, and creating a new cutting-edge gene therapy for the treatment of autoimmune uveitis.
Philip M Langer
PhD, BSc (Hons)
Postdoctoral Research Associate
Promoting myocardial regeneration via gene therapy
Research Interests
[under construction]
Recent publications
Microglia-independent rAAV-induced inflammation causes persistent ocular immune dysregulation rescued by S1P receptor modulation
Journal article
Langer PM. et al, (2026), Molecular Therapy
Characterization of the ocular inflammatory response to AAV reveals divergence by sex and age.
Journal article
Clare AJ. et al, (2025), Mol Ther, 33, 1246 - 1263
Intravitreal AAV delivery causes long-term subclinical microglia activation in mice
Conference paper
Langer PM. et al, (2023), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 64
