Contact information
robin.choudhury@cardiov.ox.ac.uk
+44 (0)1865 234664
Miss Eunice Berry
eunice.berry@cardiov.ox.ac.uk
Colleges
Websites
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British Heart Foundation Alumni Reflections Series
Professor Choudhury interviewed by BHF Associate Medical Director Professor James Leiper
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Balliol College Lectures: A Cultural History through depictions of the Heart; Botticelli to Banksy
Professor Choudhury in discussion with Dr Jennifer Sliwka, Keeper of Western Art, Ashmolean Museum
The Beating Heart.
Robin Choudhury
MA DM FRCP
Professor of Cardiovascular Medicine
- Honorary Consultant Cardiologist
- Fellow in Biomedical Sciences, Balliol
Integrative Physiology (Systems Biology)
Overview
BACKGROUND:
Robin Choudhury qualified in medicine at the University of Oxford with postgraduate training in London (Royal Brompton & Hammersmith) and at Mount Sinai School of Medicine, New York. He is Professor of Cardiovascular Medicine at the University of Oxford; Consultant Cardiologist to the John Radcliffe Hospital and Research Fellow in Biomedical Sciences at Balliol. He is an Affiliated Researcher at the Institute of Regenerative Medicine.
He is co-PI of of the NovoNordisk Foundation supported Metabolite-related inflammation and disease (MeRIAD) consortium; Joint clinical lead in the MRC-BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) and UK Chief Investigator for the ZEUS clinical trial of Ziltivekimab.
RESEARCH:
His translational science laboratory aims to understand how cells of the innate immune system are involved in processes of tissue homeostasis, injury and repair.
Areas of particular interest focus around: (1) understanding the role of monocytes, macrophages and neutrophils in acute myocardial infarction; myocardial regeneration vs repair and in atherosclerosis and (2) how bone marrow stem cells are 'programmed' e.g. by extracellular vesicles and through by genetic / epigenetic and metabolic mechanisms. The laboratory has a particular interest in hyperglycaemia-induced trained immunity.
CLINICAL PRACTICE:
Professor Choudhury has a specialist clinical interest in coronary artery disease and its management. He has particular expertise in the assessment and optimisation of cardiovascular risk factors and their interactions (e.g. cholesterol; diabetes; 'inflammation' and genetic risk).
Key publications
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis.
Journal article
Choudhury RP. et al, (2025), Cell Rep Med, 6
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.
Journal article
Edgar L. et al, (2021), Circulation, 144, 961 - 982
Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair.
Journal article
Simões FC. et al, (2020), Nat Commun, 11
Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics.
Journal article
Cahill TJ. et al, (2017), Nat Rev Drug Discov, 16, 699 - 717
Inflammatory processes in cardiovascular disease: a route to targeted therapies.
Journal article
Ruparelia N. et al, (2017), Nat Rev Cardiol, 14, 133 - 144
cute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans.
Journal article
Ruparelia N. et al, (2015), Eur Heart J, 36, 1923 - 1934
Recent publications
HDL Regulates TGFβ-Receptor Lipid Raft Partitioning, Restoring Contractile Features of Cholesterol-Loaded Vascular Smooth Muscle Cells.
Journal article
Nagesh PT. et al, (2026), JACC Basic Transl Sci, 11
Endothelial thrombomodulin-Its role in trauma-induced coagulopathy.
Journal article
Abu-Hanna J. et al, (2026), Transfusion
Trained Immunity and Cardiovascular Risk: An Immunological Perspective.
Journal article
Boden KA. et al, (2026), Immunol Rev, 337
novel in vitro model of trauma-induced endotheliopathy provides a platform for studying mechanisms of coagulopathy.
Journal article
Abu-Hanna J. et al, (2025), Blood Vessel Thromb Hemost, 2
The Beating Heart: art meets science in the story of the heart.
Journal article
Choudhury RP., (2025), Cardiovasc Res, 121, 1972 - 1974
Cardiac lymphatics retain LYVE-1-dependent macrophages during neonatal mouse heart regeneration.
Journal article
Chapman BG. et al, (2025), Nat Cardiovasc Res, 4, 1258 - 1276
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis.
Journal article
Choudhury RP. et al, (2025), Cell Rep Med, 6
Stabilisation of HIF signalling extends epicardial activation and neonatal heart regeneration
Preprint
Gamen E. et al, (2025)
C-Reactive Protein as a Potential Signpost to Trained Immunity.
Journal article
Choudhury RP., (2025), JACC Basic Transl Sci, 10
Domain-Specific Progressive Channel Dropout: Single-Source Domain Generalization for Vessel Segmentation in X-ray Coronary Angiography.
Conference paper
Atwany M. et al, (2025), Annu Int Conf IEEE Eng Med Biol Soc, 2025, 1 - 5
