We are a large multi-disciplinary department, which aims to tackle some of the world’s biggest health challenges by integrating innovative basic biology with cutting edge clinical research. We have internationally renowned programmes in a range of areas including cardiovascular sciences, diabetes and endocrinology, immunology, haematology and pathology.
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
MCCARTHY M. et al, Nature genetics
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.
Brown JM. et al, (2018), Nat commun, 9
Phenotypic and molecular characterization of a serum-free miniature erythroid differentiation system suitable for high-throughput screening and single-cell assays.
Mettananda S. et al, (2018), Exp hematol, 60, 10 - 20
Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo.
Williams RM. et al, (2018), Development, 145
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.
Wu Q. et al, (2017), Nat commun, 8
Our Clinical Facilities and Units
RDM at the Oxford IF Science + Ideas Festival
RDM researcher's will be at Oxford's own science festival over the next week: drop by our stalls and find out about genome editing, healthy eating, explore skull formation in virtual reality, and much more. (Photo credit: Martin Phelps).
Find out more about RDM at Oxford IF.