About Us
We are a large, multi-disciplinary department, which aims to tackle some of the world’s biggest health challenges by integrating innovative basic biology with cutting edge clinical research. We have internationally renowned programmes in a range of areas including cardiovascular sciences, diabetes and endocrinology, immunology, haematology and pathology.
Read moreLargest ever diabetes genetics study uncovers mechanisms behind type 2 diabetes
Genetic data from nearly a million people could find new drug targets
Read moreSpinout launch for technology that can predict heart attacks years before they happen
An Oxford University spinout led by RDM's Professor Charlambos Antoniades utilises standard CT scans to identify a potentially fatal build-up of plaques that could trigger a heart attack.
Read moreDr Kathryn Robson featured in BBC programme
Dr Robson from the MRC Weatherall Instititute of Molecular Medicine explains how a genetic mutation leads to haemetochromatosis, where people have too much iron.
Read moreLifestyle factors linked to brain health of young adults
Researchers from our Department led by Prof Paul Leeson, in collaboration with researchers from Canada and the Universities of Bristol and London, have used advanced magnetic resonance imaging to investigate whether factors such as blood pressure, fitness, smoking and alcohol intake during young adult life are associated with changes in the blood vessels inside the brain.
Read more
We are a large multi-disciplinary department, which aims to tackle some of the world’s biggest health challenges by integrating innovative basic biology with cutting edge clinical research. We have internationally renowned programmes in a range of areas including cardiovascular sciences, diabetes and endocrinology, immunology, haematology and pathology.
Latest Publications
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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
MCCARTHY M. et al, Nature genetics
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A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.
Brown JM. et al, (2018), Nat commun, 9
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Phenotypic and molecular characterization of a serum-free miniature erythroid differentiation system suitable for high-throughput screening and single-cell assays.
Mettananda S. et al, (2018), Exp hematol, 60, 10 - 20
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Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo.
Williams RM. et al, (2018), Development, 145
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In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.
Wu Q. et al, (2017), Nat commun, 8
What's new
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Dr Kathryn Robson featured in BBC programme
1 October 2018
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Lifestyle factors linked to brain health of young adults
10 September 2018
Our Clinical Facilities and Units
Cardiovascular Clinical Research Facility
Oxford Centre for Clinical Magnetic Resonance Research
MRC Molecular Haematology Unit
RDM at the Oxford IF Science + Ideas Festival
RDM researcher's will be at Oxford's own science festival over the next week: drop by our stalls and find out about genome editing, healthy eating, explore skull formation in virtual reality, and much more. (Photo credit: Martin Phelps).
Find out more about RDM at Oxford IF.