The Leducq Circadian Network (LCN) brings together basic, clinical, and translational researchers from world leading institutes across the globe to investigate how circadian biology influences cerebrovascular disease, with the aim to reveal novel targets for effective therapies.
Our aims are to understand how circadian rhythms influence stroke treatments, and reveal novel targets for effective therapies
Read our latest findings
Our network brings together researchers and clinicians from world leading institutes across the globe.
The Lecducq Circadian Network is part of the Consortium International pour la Recherche Circadienne sur l’AVC (CIRCA), which also hosts regular talks.
News and Events
Keeping an eye on circadian time
Our new paper provides guidance on best practices in measuring and distinguishing endogenous
circadian rhythms from time-of-day rhythms in clinical research and medicine.
Russell Foster features on The Next Big Idea Podcast
Listen to How Understanding Your Body’s Clock Can Revolutionize Your Health
Diurnal Differences in Immune Response
New paper in Stroke: Esposito et al. Diurnal Differences in Immune Response in Brain, Blood and Spleen After Focal Cerebral Ischemia in Mice. Stroke. 2022;53:e507–e511
Nature Reviews Neurology review article
Tiedt et al. The neurovascular unit and systemic biology in stroke - implications for translation and treatment. Nat Rev Neurol. 2022 Oct;18(10):597-612.
Mandeville et al. Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases. Stroke. 2022 Oct 12