Publications — Radcliffe Department of Medicine

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Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs in silico Prediction of a Network-Based Rationale for Therapy.

Singh K. et al, (2021), Front Immunol, 12

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Moreira LM. et al, (2020), Nature, 587, 460 - 465

Calcitonin paracrine signaling controls atrial fibrogenesis and arrhythmia

MOREIRA LM. et al, (2020), Nature

Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction.

Darlot B. et al, (2020), J Biol Chem, 295, 10926 - 10939

Early Embryonic Expression of AP-2α Is Critical for Cardiovascular Development.

Johnson A-L. et al, (2020), J Cardiovasc Dev Dis, 7

Characterization of a novel inhibitor of coagulation factor XIa identified from salivary gland transcripts of the lone star tick, Amblyomma americanum.

Mrinalini None. et al, (2020), Toxicon, 177 Suppl 1

Using evasins to target the chemokine network in inflammation.

Bhattacharya S. and Kawamura A., (2020), Adv Protein Chem Struct Biol, 119, 1 - 38

Using evasins to target the chemokine network in inflammation

KAWAMURA A. and BHATTACHARYA S., (2019), Advances in Protein Chemistry and Structural Biology: Inflammatory Disorders, Part A

Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines

Bhusal RP. et al, (2019), Trends in Biochemical Sciences

A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.

Lee AW. et al, (2019), J Biol Chem, 294, 11199 - 11212

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

Gao R. et al, (2019), Cell Res, 29, 486 - 501

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

Gorman KM. et al, (2019), Am J Hum Genet, 104, 948 - 956

IDENTIFICATION OF THE MAJOR GENETIC CONTRIBUTORS TO TETRALOGY OF FALLOT

Page DJ. et al, (2019), HEART, 105, A182 - A183

Biowire Model of Interstitial and Focal Cardiac Fibrosis

Wang EY. et al, (2019), ACS Central Science

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation.

Bailey J. et al, (2018), Sci Rep, 8

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

Dykes IM. et al, (2018), Sci Rep, 8

Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.

Alenazi Y. et al, (2018), Sci Rep, 8

The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins.

Eaton JRO. et al, (2018), J Biol Chem, 293, 6134 - 6146

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.

Singh K. et al, (2017), Sci Rep, 7

Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.

Szumska D. et al, (2017), BMC Dev Biol, 17

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