Publications — Radcliffe Department of Medicine

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Phylogenetic Analysis Indicates That Evasin-Like Proteins of Ixodid Ticks Fall Into Three Distinct Classes

BHATTACHARYA S. and NUTTALL PA., (2021), Frontiers in Cellular and Infection Microbiology, 11

Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs in silico Prediction of a Network-Based Rationale for Therapy.

Singh K. et al, (2021), Front Immunol, 12

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Moreira LM. et al, (2020), Nature, 587, 460 - 465

Calcitonin paracrine signaling controls atrial fibrogenesis and arrhythmia

MOREIRA LM. et al, (2020), Nature

Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction.

Darlot B. et al, (2020), J Biol Chem, 295, 10926 - 10939

Early Embryonic Expression of AP-2α Is Critical for Cardiovascular Development.

Johnson A-L. et al, (2020), J Cardiovasc Dev Dis, 7

Characterization of a novel inhibitor of coagulation factor XIa identified from salivary gland transcripts of the lone star tick, Amblyomma americanum.

Mrinalini None. et al, (2020), Toxicon, 177 Suppl 1

Using evasins to target the chemokine network in inflammation.

Bhattacharya S. and Kawamura A., (2020), Adv Protein Chem Struct Biol, 119, 1 - 38

Using evasins to target the chemokine network in inflammation

KAWAMURA A. and BHATTACHARYA S., (2019), Advances in Protein Chemistry and Structural Biology: Inflammatory Disorders, Part A

Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines

Bhusal RP. et al, (2019), Trends in Biochemical Sciences

A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.

Lee AW. et al, (2019), J Biol Chem, 294, 11199 - 11212

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

Gao R. et al, (2019), Cell Res, 29, 486 - 501

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

Gorman KM. et al, (2019), Am J Hum Genet, 104, 948 - 956

IDENTIFICATION OF THE MAJOR GENETIC CONTRIBUTORS TO TETRALOGY OF FALLOT

Page DJ. et al, (2019), HEART, 105, A182 - A183

Biowire Model of Interstitial and Focal Cardiac Fibrosis

Wang EY. et al, (2019), ACS Central Science

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation.

Bailey J. et al, (2018), Sci Rep, 8

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

Dykes IM. et al, (2018), Sci Rep, 8

Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.

Alenazi Y. et al, (2018), Sci Rep, 8

The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins.

Eaton JRO. et al, (2018), J Biol Chem, 293, 6134 - 6146

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.

Singh K. et al, (2017), Sci Rep, 7

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