Zhengkun Chen
PhD
Novo Nordisk Postdoctoral Research Fellow
Zhengkun is a Novo Nordisk Postdoctoral Research Fellow in the research group of Professor Dame Molly Stevens at the University of Oxford. He earned his PhD in Chemistry from the University of Toronto, where his research focused on developing biomimetic materials and microfluidic devices to construct advanced in vitro skin models as alternatives to animal testing. Before pursuing his doctoral studies, he graduated with first-class honours in Biomedical Engineering from the Hong Kong Polytechnic University. His current research is dedicated to engineering human cardiac organoids as advanced platforms for disease modelling and drug screening. By integrating cutting-edge biomaterials, microfluidic technologies, and machine learning approaches, Zhengkun aims to enhance the physiological relevance, predictive power, and throughput of organoid systems. His work seeks to bridge the gap between in vitro models and human physiology, paving the way for more effective and personalized therapeutic strategies.
Recent publications
Spheroid-based skin-on-a-chip platform for the evaluation of the toxicity of small molecules and nanoparticles.
Journal article
Kalhori D. et al, (2025), Lab Chip, 25, 4038 - 4047
Hydrodynamically generated multilayer skin spheroids enable in vitro screening of biologically active ingredients and toxicity tests.
Journal article
Chen Z. et al, (2025), Sci Adv, 11
Nanocolloidal hydrogel mimics the structure and nonlinear mechanical properties of biological fibrous networks.
Journal article
Prince E. et al, (2023), Proc Natl Acad Sci U S A, 120
Printing Structurally Anisotropic Biocompatible Fibrillar Hydrogel for Guided Cell Alignment.
Journal article
Chen Z. et al, (2022), Gels, 8
