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Contact information
Surawee Chuaiphichai
BSc (Hons), DPhil
Postdoctoral Research Scientist
I am a postdoctoral research fellow in Prof Keith Channon's laboratory in the Division of Cardiovascular Medicine. I completed my DPhil in 2014 in which I studied the role of endothelial cell Gch1 and tetrahydrobiopterin (BH4) biosynthesis in vascular function and blood pressure regulation. I am currently investigating the role of endothelial cell BH4-dependent NOS regulation in vascular adaptations and blood pressure regulation in normal pregnancy using a novel mouse model of endothelial cell BH4 deficiency (endothelial cell-targeted Gch1 knockout mouse).
Recent publications
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Novel Role of 5-Methyl-(6S)-Tetrahydrofolate in Mediating Endothelial Cell Tetrahydrobiopterin in Pregnancy and Implications for Gestational Hypertension.
Journal article
Dickinson Y. et al, (2024), Hypertension
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Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
Journal article
Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890
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Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury.
Journal article
Chuaiphichai S. et al, (2023), Am J Physiol Heart Circ Physiol, 324, H430 - H442
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PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Journal article
Wood A. et al, (2023), Cardiovasc Res, 119, 599 - 610
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Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
Journal article
Chuaiphichai S. et al, (2023), Vascul Pharmacol, 150