Surawee Chuaiphichai
BSc (Hons), DPhil
Postdoctoral Research Scientist
I am a postdoctoral research fellow in Prof Keith Channon's laboratory in the Division of Cardiovascular Medicine. I completed my DPhil in 2014 in which I studied the role of endothelial cell Gch1 and tetrahydrobiopterin (BH4) biosynthesis in vascular function and blood pressure regulation. I am currently investigating the role of endothelial cell BH4-dependent NOS regulation in vascular adaptations and blood pressure regulation in normal pregnancy using a novel mouse model of endothelial cell BH4 deficiency (endothelial cell-targeted Gch1 knockout mouse).
Recent publications
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Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Journal article
Douglas G. et al, (2018), Cardiovasc Res, 114, 1385 - 1399
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Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm.
Journal article
Chuaiphichai S. et al, (2018), Hypertension, 72, 128 - 138
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Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Journal article
Patel J. et al, (2018), Vascul Pharmacol
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A new role for RGS-1 in vascular function and blood pressure regulation
Conference paper
Patel J. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S88 - S88
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Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II
Conference paper
Chuaiphichai S. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S90 - S90