BSc (Hons), DPhil
Postdoctoral Research Scientist
I am a postdoctoral research fellow in Prof Keith Channon's laboratory in the Division of Cardiovascular Medicine. I completed my DPhil in 2014 in which I studied the role of endothelial cell Gch1 and tetrahydrobiopterin (BH4) biosynthesis in vascular function and blood pressure regulation. I am currently investigating the role of endothelial cell BH4-dependent NOS regulation in vascular adaptations and blood pressure regulation in normal pregnancy using a novel mouse model of endothelial cell BH4 deficiency (endothelial cell-targeted Gch1 knockout mouse).
Roles for Endothelial Cell and Macrophage Gch1 and Tetrahydrobiopterin in Atherosclerosis Progression.
Douglas G. et al, (2018), Cardiovasc Res
A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
Chuaiphichai S. et al, (2017), Br J Pharmacol, 174, 657 - 671
Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension.
Chuaiphichai S. et al, (2016), Vascul Pharmacol, 77, 69 - 79
The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy
Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Latremoliere A. et al, (2015), Neuron, 86, 1393 - 1406