Surawee Chuaiphichai

• A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.

  Chuaiphichai S. et al, (2017), Br J Pharmacol, 174, 657 - 671

• Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension.

  Chuaiphichai S. et al, (2016), Vascul Pharmacol, 77, 69 - 79

• The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

  Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775

• Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.

  Latremoliere A. et al, (2015), Neuron, 86, 1393 - 1406

• Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.

  McNeill E. et al, (2015), Free Radic Biol Med, 79, 206 - 216

• NOS/redox-independent protective effects of GTP cyclohydrolase 1 (GCH1) overexpression and tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

  Hijazo RC. et al, (2014), EUROPEAN HEART JOURNAL, 35, 1185 - 1186

• Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

  Chuaiphichai S. et al, (2014), Hypertension, 64, 530 - 540

• P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.

  Duglan D. et al, (2014), Cardiovasc Res, 103 Suppl 1

• 303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

  Chuaiphichai S. et al, (2014), Cardiovasc Res, 103 Suppl 1

• 201 Regulation of INOS Function, Redox State and NRF2 Activation by Macrophage GCH1 and Tetrahydrobiopterin.

  McNeill E. et al, (2014), Heart, 100 Suppl 3, A110 - A111

• Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation.

  Cardini B. et al, (2014), PLoS One, 9

• A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.

  Benson MA. et al, (2013), J Biol Chem, 288, 29836 - 29845

• The relative contributions of cardiomyocytes versus endothelial cells to cardiac BH4 production; studies in novel cardiomyocyte- and endothelial-specific GTPCH I-deficient mice

  Bendall J. et al, (2012), NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 27, S29 - S29

• Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo

  McNeill E. et al, (2012), NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 27, S41 - S41

Recent Publications

• A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.

  Chuaiphichai S. et al, (2017), Br J Pharmacol, 174, 657 - 671

• Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension.

  Chuaiphichai S. et al, (2016), Vascul Pharmacol, 77, 69 - 79

• The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

  Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775

• Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.

  Latremoliere A. et al, (2015), Neuron, 86, 1393 - 1406

• Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.

  McNeill E. et al, (2015), Free Radic Biol Med, 79, 206 - 216