Contact information
+44 (0)1865 857253
Ruth Coleman
MSc
Head of Statistics & Modelling Group
Ruth is the Head of Statistics and Modelling Group, responsible for the management of the unit’s statistical output, maintaining transparency and presenting results in an impartial and objective manner.
In her time in the DTU she has gained extensive experience in the design, analysis and reporting of phase 2-4 trials with a focus on large scale cardiovascular outcome trials including TECOS, EXSCEL and ACE. Outside of trial work, the group use data from both randomized controlled trials and observational studies to evaluate diabetes-related complications and mortality, and produce validated prediction models to contribute to the improvement of outcomes in people with diabetes.
Her ongoing projects include the expansion of the UKPDS Risk Engine to include estimates of both cardiovascular and microvascular disease risk, and modelling life expectancy in type 2 diabetes.
She is currently a co-investigator on the UKPDS Legacy Study and the statistical lead for the ACE trial.
Recent publications
Estimating the risk of cardiovascular outcomes and all-cause mortality in individuals with type 2 diabetes: Validation of the UKPDS outcomes model using TECOS and EXSCEL data.
Journal article
Coleman RL. et al, (2026), Diabetes Obes Metab, 28, 1068 - 1075
International Variation in Case Fatality After Major Coronary or Cerebrovascular Events in Individuals With Type 2 Diabetes: Evidence From ADVANCE, TECOS, and EXSCEL.
Journal article
Clarke PM. et al, (2025), Diabetes Care, 48, 1925 - 1931
Assessing the efficacy, safety and utility of hybrid closed-loop glucose control compared with standard insulin therapy combined with continuous glucose monitoring in young people (≥16 years) and adults with cystic fibrosis-related diabetes (CL4P-CF study): protocol for an open-label, multicentre, randomised, two-arm and single-period parallel trial
Journal article
Kadiyala N. et al, (2025), BMJ Open, 15
Impact of changes in conventional risk factors induced by once-weekly GLP-1 receptor agonist exenatide on cardiovascular outcomes: an EXSCEL post hoc analysis.
Journal article
Coleman RL. et al, (2025), Cardiovasc Diabetol, 24
Glucocorticoid-induced hyperglycaemia in hospitalised adults: A matched cohort study (2013-2023).
Journal article
Golubic R. et al, (2025), Diabetes Obes Metab, 27, 3635 - 3644
