Contact information
George Harston
DPhil, MA, MBBChir, MRCP
Consultant physician
- Acute General Medicine, Geratology and Stroke Medicine
George Harston is a Consultant Physician in Stroke and Internal Medicine at Oxford University Hospitals and Chief Medical & Innovation Officer at Brainomix. He is a clinical academic and MedTech industry leader with a track record in developing, validating, and deploying AI imaging software across stroke, interstitial lung disease (ILD), and oncology. He led the largest-ever prospective evaluation of stroke imaging AI through the NHS AI in Health and Care Award. He has driven widespread clinical adoption of AI imaging technologies and informed national stroke guidelines.
At Brainomix, he leads translational medicine, product management, medical affairs, and the Life Sciences business unit. He also established and oversees a US-based expert imaging core lab supporting academic and industry clinical trials.
Dr Harston maintains an active research and teaching portfolio, supervises doctoral and postgraduate trainees. He serves on the Editorial Board of Neuroimage: Stroke and the Board of Directors (as Chair) of the Open Source Imaging Consortium for ILD. His research focusses on acute neuroimaging in stroke and interstitial lung diseases, with a particular interest in CT and MRI methodologies, including non-contrast metabolic and perfusion imaging.
Dr Harston was awarded my medical degree from the University of Cambridge in 2006. He completed his DPhil in Clinical Medicine in 2015, before taking up a Clinical Lecturer position later that year. He was appointed as a Consultant Physician in Acute General Medicine, Geratology and Stroke Medicine at Oxford University Hospitals NHS Foundation Trust in 2018, and as Chief Medical and Innovation Officer at Brainomix, a spin-out company from the University of Oxford.
Recent publications
Optimizing Reperfusion Trials: A Consensus Research Roadmap From the STAIR XIII Conference.
Journal article
Campbell BCV. et al, (2026), Stroke, 57, 514 - 525
ificial Intelligence and Novel Trial Designs for Acute Ischemic Stroke: Opportunities and Challenges.
Journal article
Broderick JP. et al, (2026), Stroke, 57, 265 - 274
Neuroimaging of acute myocardial injury in stroke: insights into brain lesion locations and network disconnections.
Journal article
Mikulenka P. et al, (2026), Front Neurol, 17
CT perfusion for lesion-symptom mapping in large vessel occlusion ischemic stroke.
Journal article
Garrard JW. et al, (2025), J Neurointerv Surg, 18, 149 - 154
ificial Intelligence-Driven Detection of Large Vessel Occlusions on NCCT: A Multi-Institutional Study.
Journal article
Rai AT. et al, (2025), AJNR Am J Neuroradiol, 46, 2528 - 2534
ificial intelligence imaging decision support for acute stroke treatment in England: a prospective observational study.
Journal article
Nagaratnam K. et al, (2025), Lancet Digit Health, 7
Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion in Anterior Circulation: Results of a 3-Month Follow-up of a Prospective, Open Label, Single-Center Study.
Journal article
Staszewski J. et al, (2025), Transl Stroke Res, 16, 1931 - 1946
Corticospinal tract damage on baseline CT predicts motor recovery and functional outcome in intracerebral haemorrhage.
Journal article
Murray ON. et al, (2025), Eur Stroke J, 10, 1383 - 1391
Thrombolysis With Tenecteplase for Minor Disabling Stroke: Secondary Analysis of the TEMPO-2 Randomized Clinical Trial.
Journal article
Zhang Y. et al, (2025), JAMA Neurol, 82, 1243 - 1250
bstract 295: Prospective comparison of core and penumbra volumes from two CT perfusion quantification software packages
Journal article
Wolfe J. et al, (2025), Stroke (Hoboken, N.J.), 5
Prospective Evaluation of Artificial Intelligence Imaging Support Software for Acute Ischemic Stroke in the Mayo Clinic Telestroke Network.
Journal article
Smith BH. et al, (2025), Mayo Clin Proc Innov Qual Outcomes, 9
Sex Differences in Outcomes After Tenecteplase for Minor Stroke: A Subanalysis of the TEMPO-2 Trial.
Journal article
Yu AYX. et al, (2025), J Am Heart Assoc, 14
Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion.
Journal article
Goyal M. et al, (2025), N Engl J Med, 392, 1385 - 1395
mated CT angiography collateral scoring in anterior large vessel occlusion stroke: A multireader study.
Journal article
Jabal MS. et al, (2025), Interv Neuroradiol, 31, 95 - 100
ificial intelligence assisted detection of large vessel occlusion on CT angiography in acute stroke patients: a multi-reader multi-case study
Journal article
Nagaratnam K. et al, (2025), BJR|Artificial Intelligence, 2
matically quantified follow-up imaging biomarkers predict clinical outcomes after acute ischemic stroke.
Journal article
Abraham S. et al, (2025), Front Neurol, 16
Evaluation of e-Lung automated quantitative computed tomography biomarkers in idiopathic pulmonary fibrosis.
Journal article
George PM. et al, (2024), ERJ Open Res, 10
Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial.
Journal article
Coutts SB. et al, (2024), Lancet, 403, 2597 - 2605
e-Lung Computed Tomography Biomarker Stratifies Patients at Risk of Idiopathic Pulmonary Fibrosis Progression in a 52-Week Clinical Trial.
Journal article
Devaraj A. et al, (2024), Am J Respir Crit Care Med, 209, 1168 - 1169
Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke.
Journal article
Samaniego EA. et al, (2023), Stroke, 54, 3190 - 3201
Investigation of relayed nuclear Overhauser enhancement effect at -1.6 ppm in an ischemic stroke model.
Journal article
Foo LS. et al, (2023), Quant Imaging Med Surg, 13, 7879 - 7892
bstract 006: Glenzocimab Is Associated With Less Haemorrhagic Transformation Using Artificial Intelligence Imaging In Mechanical Thrombectomy Patients
Journal article
Comenducci A. et al, (2023), Stroke (Hoboken, N.J.), 3
Reduced Left Atrial Rotational Flow Is Independently Associated With Embolic Brain Infarcts.
Journal article
Spartera M. et al, (2023), JACC Cardiovasc Imaging, 16, 1149 - 1159
Posterior circulation ischaemic stroke diagnosis and management.
Journal article
Schneider AM. et al, (2023), Clin Med (Lond), 23, 219 - 227
Transitioning from clinical cardiology to industry: general considerations.
Journal article
Daniels MJ. et al, (2023), Heart, 109, 330 - 331
ificial intelligence-based decision support software to improve the efficacy of acute stroke pathway in the NHS: an observational study.
Journal article
Nagaratnam K. et al, (2023), Front Neurol, 14
Impact of e-ASPECTS software on the performance of physicians compared to a consensus ground truth: a multi-reader, multi-case study.
Journal article
Kobeissi H. et al, (2023), Front Neurol, 14
Quantitative chemical exchange saturation transfer imaging of nuclear overhauser effects in acute ischemic stroke.
Journal article
Msayib Y. et al, (2022), Magn Reson Med, 88, 341 - 356
Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine.
Journal article
Evans NR. et al, (2022), Int J Stroke, 17, 251 - 259
Interpretable Machine Learning Modeling for Ischemic Stroke Outcome Prediction.
Journal article
Jabal MS. et al, (2022), Front Neurol, 13
Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients With Acute Ischemic Stroke Due to Large Vessel Occlusion: Study Protocol for a Prospective, Open Label, Single-Center Study With 12 Months of Follow-Up.
Journal article
Staszewski J. et al, (2022), Front Neurol, 13
Improved Stroke Care in a Primary Stroke Centre Using AI-Decision Support.
Journal article
Gunda B. et al, (2022), Cerebrovasc Dis Extra, 12, 28 - 32
mated quantification of atrophy and acute ischemic volume for outcome prediction in endovascular thrombectomy.
Journal article
Kis B. et al, (2022), Front Neurol, 13
Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial.
Journal article
Al-Shahi Salman R. et al, (2021), JAMA Neurol, 78, 1179 - 1186
Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiority trial.
Journal article
SoSTART Collaboration ., (2021), Lancet Neurol, 20, 842 - 853
Clinical translation of amide proton transfer (APT) MRI for ischemic stroke: a systematic review (2003-2020).
Journal article
Foo LS. et al, (2021), Quant Imaging Med Surg, 11, 3797 - 3811
Noncontrast Computed Tomography e-Stroke Infarct Volume Is Similar to RAPID Computed Tomography Perfusion in Estimating Postreperfusion Infarct Volumes.
Journal article
Bouslama M. et al, (2021), Stroke, 52, 634 - 641
Innovative use of artificial intelligence and digital communication in acute stroke pathway in response to COVID-19.
Journal article
Nagaratnam K. et al, (2020), Future Healthc J, 7, 169 - 173
Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study.
Journal article
McGarry BL. et al, (2020), J Cent Nerv Syst Dis, 12
Partial volume correction for quantitative CEST imaging of acute ischemic stroke.
Journal article
Msayib Y. et al, (2019), Magn Reson Med, 82, 1920 - 1928
ICA-based denoising for ASL perfusion imaging.
Journal article
Carone D. et al, (2019), Neuroimage, 200, 363 - 372
Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain.
Journal article
Knight MJ. et al, (2019), Biomed Spectrosc Imaging, 8, 11 - 28
Prospects for investigating brain oxygenation in acute stroke: Experience with a non-contrast quantitative BOLD based approach.
Journal article
Stone AJ. et al, (2019), Hum Brain Mapp, 40, 2853 - 2866
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.
Journal article
Al-Shahi Salman R. et al, (2019), Lancet Neurol, 18, 643 - 652
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial.
Journal article
RESTART Collaboration ., (2019), Lancet, 393, 2613 - 2623
Measurement of collateral perfusion in acute stroke: a vessel-encoded arterial spin labeling study.
Journal article
Okell TW. et al, (2019), Sci Rep, 9
Quantifying T 2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients.
Journal article
Damion RA. et al, (2019), Phys Med Biol, 64
Letter by Harston et al Regarding Article, "Alberta Stroke Program Early CT Score Versus Computed Tomographic Perfusion to Predict Functional Outcome After Successful Reperfusion in Acute Ischemic Stroke".
Journal article
Harston G. et al, (2019), Stroke, 50
Quantitative CEST imaging of amide proton transfer in acute ischaemic stroke.
Journal article
Msayib Y. et al, (2019), Neuroimage Clin, 23
Collateral Automation for Triage in Stroke: Evaluating Automated Scoring of Collaterals in Acute Stroke on Computed Tomography Scans.
Journal article
Grunwald IQ. et al, (2019), Cerebrovasc Dis, 47, 217 - 222
Quantifying Infarct Growth and Secondary Injury Volumes: Comparing Multimodal Image Registration Measures.
Journal article
Harston GWJ. et al, (2018), Stroke, 49, 1647 - 1655
The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial.
Journal article
Al-Shahi Salman R. et al, (2018), Trials, 19
Optimizing image registration and infarct definition in stroke research.
Journal article
Harston GWJ. et al, (2017), Ann Clin Transl Neurol, 4, 166 - 174
Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling.
Journal article
Harston GWJ. et al, (2017), Stroke, 48, 123 - 130
Serial quantification of brain oxygenation in acute stroke using streamlined-qBOLD
Journal article
Stone A. et al, (2017)
Imaging biomarkers in acute ischemic stroke trials: a systematic review.
Journal article
Harston GWJ. et al, (2015), AJNR Am J Neuroradiol, 36, 839 - 843
Identifying the ischaemic penumbra using pH-weighted magnetic resonance imaging.
Journal article
Harston GWJ. et al, (2015), Brain, 138, 36 - 42
Quantification of amide proton transfer effect pre- and post-gadolinium contrast agent administration.
Journal article
Tee YK. et al, (2014), J Magn Reson Imaging, 40, 832 - 838
Quantification of amide proton transfer effect pre-And post-gadolinium contrast agent administration
Journal article
Tee YK. et al, (2014), Journal of Magnetic Resonance Imaging, 40, 832 - 838
Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients.
Journal article
Tee YK. et al, (2014), NMR Biomed, 27, 1019 - 1029
Emergency medicine research: rites, rituals and consent.
Journal article
Harston GWJ. et al, (2014), Emerg Med J, 31, 90 - 91
Emergency medicine research: Rites, rituals and consent
Journal article
Harston GWJ. et al, (2014), Emergency Medicine Journal, 31, 90 - 91
Lacunar infarction associated with anabolic steroids and polycythemia: a case report.
Journal article
Harston GWJ. et al, (2014), Case Rep Neurol, 6, 34 - 37
Ventricular extension of intracerebral hemorrhage during intravenous thrombolysis.
Journal article
Harston GWJ. et al, (2013), Cerebrovasc Dis, 36, 324 - 325
Diffusion tensor imaging to identify structural change following lacunar stroke
Conference paper
Harston GWJ. et al, (2013), CEREBROVASCULAR DISEASES, 35, 70 - 70
Tissue outcome in acute ischemic stroke: how useful is perfusion?
Conference paper
Harston GWJ. et al, (2013), CEREBROVASCULAR DISEASES, 35, 415 - 415
pH-weighted imaging in acute stroke: can metabolic imaging help us better understand the penumbra?
Conference paper
Harston GWJ. et al, (2013), CEREBROVASCULAR DISEASES, 35, 46 - 46
Reducing door-to-consent time: neuroradiographers as key witnesses
Conference paper
Semple JC. et al, (2013), CEREBROVASCULAR DISEASES, 35, 198 - 198
Imaging Surrogates in Acute Stroke Trials: a Systematic Review
Conference paper
Harston GWJ. et al, (2013), CEREBROVASCULAR DISEASES, 35, 418 - 418
The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: a review of rtPA neurotoxicity.
Journal article
Harston GWJ. et al, (2010), J Cereb Blood Flow Metab, 30, 1804 - 1816
The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: A review of rtPA neurotoxicity
Journal article
Harston GWJ. et al, (2010), Journal of Cerebral Blood Flow and Metabolism, 30, 1804 - 1816
Spatiotemporal receptive field properties of a looming-sensitive neuron in solitarious and gregarious phases of the desert locust.
Journal article
Rogers SM. et al, (2010), J Neurophysiol, 103, 779 - 792
