My research interests are focused on using existing tools to do genome wide association analysis, devise ways to handle large datasets, build databases and make the results easily accessible to our collaborators.
I am currently involved in next generation exome sequencing data analysis to discover susceptibility genes for cardiovascular disease.
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
Nüesch E. et al, (2016), Int j epidemiol, 45, 1927 - 1937
Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.
Huffman JE. et al, (2015), Blood, 126, e19 - e29
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.
Interleukin 1 Genetics Consortium None., (2015), Lancet diabetes endocrinol, 3, 243 - 253
Genetic studies of body mass index yield new insights for obesity biology.
Locke AE. et al, (2015), Nature, 518, 197 - 206
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D. et al, (2015), Nature, 518, 187 - 196