My research interests are focused on using existing tools to do genome wide association analysis, devise ways to handle large datasets, build databases and make the results easily accessible to our collaborators.
I am currently involved in next generation exome sequencing data analysis to discover susceptibility genes for cardiovascular disease.
Differential Gene Expression in Macrophages From Human Atherosclerotic Plaques Shows Convergence on Pathways Implicated by Genome-Wide Association Study Risk Variants.
Chai JT. et al, (2018), Arterioscler thromb vasc biol, 38, 2718 - 2730
Neonatal Micro-RNA Profile Determines Endothelial Function in Offspring of Hypertensive Pregnancies.
Yu GZ. et al, (2018), Hypertension, 72, 937 - 945
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou E. et al, (2018), Nat genet, 50, 1412 - 1425
Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.
Ehsan M. et al, (2018), J mol cell cardiol, 121, 287 - 296
Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer's disease.
Grace C. et al, (2018), Sci rep, 8