Contact information
Antonio Rodríguez-Romera
DPhil Student
DPhil Student in Megakaryocyte Biology
I'm a DPhil student in Beth Psaila's lab. My research focus on megkarycoytes, fascinating bone marrow cells that are primarily responsible for platelet production. These cells have the unusual ability to accumulate several copies of their own genomic DNA during maturation, becoming polyploid. In my studies I use a combination of computational and experimental techniques to understand how megakaryocytes regulate their cell cycle during maturation and the consequences of polyploidization on megakaryocyte biology.
Recent publications
proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.
Journal article
Li R. et al, (2024), Sci Transl Med, 16
The bone marrow is the primary site of thrombopoiesis.
Journal article
Asquith NL. et al, (2024), Blood, 143, 272 - 278
pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis
Preprint
Li R. et al, (2023)
Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms
Conference paper
Li R. et al, (2022), BLOOD, 140, 1091 - 1092