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Alexandra Preston
PhD
Postdoctoral Scientist
Erythropoiesis is metabolically regulated and environmentally sensitive. Characterisation of these processes is required to understand the conditions required for appropriate red blood cell production. I take genomic, cellular and metabolic approaches to answer questions in this context.
Before joining the Drakesmith group with a MRC WIMM scholarship, I graduated from the University of Bath in 2017 with a 1st class BSc(Hons) in Biology. Here I had the great pleasure of working with Professor David Tosh and Professor Tony Perry. I also spent a year at the Garvan Institute of Medical Research, Sydney, during my undergraduate degree.
Publications
Plasma iron controls neutrophil production and function
Frost J. et al, (2021), Science Advances
Adaptive immunity and vaccination – iron in the spotlight
Preston A. et al, (2021), Immunotherapy Advances, 1
Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection
Frost J. et al, (2021), Med, 2
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases
Jurczyluk J. et al, (2016), Immunol Cell Biol, 94