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Aideen O'Neill

MBBS MRCP FRCPath

Post-Doctoral Researcher

I am a clinical haematologist and post-doctoral researcher in the haematopoietic transplantation and immunotherapy group of Prof. Ronjon Chakraverty. I recently completed my DPhil, funded by an MRC Clinical Research Training Fellowship  (first supervisor: Prof. Chakraverty; second supervisor: Prof. Cristina Lo Celso (Imperial College/ Francis Crick Institute).  Through my DPhil, I investigated the potential role of the bone marrow stroma in supporting T cells.  

Prior to this, I completed my undergraduate degree in medicine at University College London.  After qualifying I was awarded an NIHR Academic Foundation Post at UCL and an Academic Clinical Fellowship, also at UCL.   I am a fellow of the Royal College of Pathologists.

I am interested in the potential to target bone marrow stromal changes as a route to improving adoptively-transferred T cell and molecular anti-leukaemia therapies. 

Confocal image of bone marrow LepR+ MSCs (in green) as delineated using a reporter for LepR; blood vessels are shown in red; collected using a x40 objective at 0.75 um intervals in the Z plane.