Colleges
Contact information
Aaron Johnston
BA (Hons)
DPhil Student
I am a medical student intercalating a DPhil in Cardiovascular Science funded by a scholarship from the British Heart Foundation. I studied Medical Sciences at the University of Oxford and graduated with a First Class Honours, ranking top of the cohort in the 1st Bachelor of Medicine examinations.
Now in my final year of DPhil study, my work aims to generate insight into the drivers of cardiac fibrosis, a process that is key in the initiation and progression of atrial fibrillation (the most common hearth rhythm disturbance). By combining high-throughput phenotypic screening, AI-aided drug prediction and a range of cell/molecular biology techniques, this work aims to identify novel therapeutic candidates for the treatment of atrial fibrillation-associated cardiac fibrosis.
Alongside my DPhil studies, I am also the Student Representative for the university's Medical Sciences Doctoral Training Centre and a member of the Radcliffe Department of Medicine's Researcher Association. I also tutor Undergraduate Medical Students in Cardiovascular Pathology and Physiology.
Key publications
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Single-nucleus multi-omics implicates androgen receptor signaling in cardiomyocytes and NR4A1 regulation in fibroblasts during atrial fibrillation.
Journal article
Leblanc FJA. et al, (2025), Nat Cardiovasc Res
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Tracking endothelium-dependent NO release in pressurized arteries.
Journal article
Wallis L. et al, (2023), Front Physiol, 14
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Aging-associated mechanisms of atrial fibrillation progression and their therapeutic potential
Journal article
Zhao S. et al, (2024), Journal of Cardiovascular Aging, 4
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Dysfunctional atrial fibroblast processing of filamin A in atrial fibrillation
Journal article
Johnston AM. et al, (2024), European Heart Journal, 45
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Decoding Long Noncoding RNAs in Myocardial Infarction: A Step Closer to a "Magic Bullet"?
Journal article
Johnston AM. et al, (2024), Can J Cardiol
