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Colleges
Ye Wei
BSc PhD
Postdoctoral Researcher
About
I am a postdoctoral researcher in the Davies and Hughes groups, working at the intersection of computational modelling and genome biology. A key question driving my research is what determines the formation of physical interactions between cis-regulatory elements, and whether these interactions are predictive of - or causally linked to - gene expression outcomes. To address this, I develop deep learning models that learn from base-pair resolution chromatin contact data generated by Micro Capture-C.
Before joining Oxford, I completed my PhD in computer science, where I worked on deep learning, spatiotemporal modeling, and representation learning across several scientific domains. These experiences gave me a broad computational toolkit that I now apply to open questions in genome biology. I am particularly drawn to building interpretable models that go beyond prediction to offer mechanistic insight into genome function.