Wei Gan
PhD
Postdoctoral researcher
My current research is focused on using large-scale genetic data such as T2D-GENES /GoT2D/DIAGRAM Consortium, UK Biobank and China Kadoorie Biobank obtained from next-generation sequencing and GWAS approaches to 1) identify and characterise genetic variants influencing predisposition to type 2 diabetes and its related traits; 2) investigation the causal relationship between an exposure or intermediate phenotype and type 2 diabetes/cardiovascular diseases using Mendelian randomisation approaches; 3) identify genetic factors contributing to weight loss after bariatric surgery procedures. I received my Ph.D degree at the Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. In 2014, I joined Professor Mark McCarthy's group as postdoc researcher. I'm now also collaborating with Prof Rachel Batterham at UCLH and Professor Zhengming Chen at CTSU, Oxford University.
Recent publications
TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.
Journal article
Walth-Hummel AA. et al, (2026), Nat Commun, 17
Interpretable machine learning leverages proteomics to improve cardiovascular disease risk prediction and biomarker identification.
Journal article
Climente-González H. et al, (2025), Commun Med (Lond), 5
Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.
Journal article
Pozarickij A. et al, (2024), Nat Commun, 15
Iron Status and Risk of Heart Disease, Stroke, and Diabetes: A Mendelian Randomization Study in European Adults.
Journal article
Liu Y. et al, (2024), J Am Heart Assoc, 13
Genetics of skeletal proportions in two different populations.
Journal article
Bartell E. et al, (2023), bioRxiv
