RDM scientists develop new method that uses a marine coral protein to visualise calcium flow through heart muscle fibres.
The image shows (at x2000 magnification) a single heart muscle cell: the red calcium indicator lines up precisely between the green stripes, which mark where the muscles’ contractive machinery is anchored. In every heartbeat, the distance between the green bands (which are just 2 micrometres apart, or about 1/40 the thickness of a human hair) reduces by just 10%, so all heart muscle cells need to contract together to pump blood – normal calcium activity is essential for this synchronization (Image credit: Paul Robinson).
MRC MHU
NDCLS
Principal Investigators
WIMM
MA; MBBS; MRCP; FRCPath; PhD Bethan Psaila - Associate Professor of Haematology
MRC MHU
Students
Eva Thielecke - Visiting Student
MRC MHU
NDCLS
OCH
Principal Investigators
WIMM
MRCP FRCP FRCPath Paresh Vyas - Professor of Haematology
MRC MHU
MRC TIDU
NDCLS
Principal Investigators
Research Support
WIMM
BSc (Hons) DPhil Christian Babbs - Head of Genome Engineering/Principal Investigator in RDM
MRC MHU
NDCLS
Researchers
Matthew Gosden - DPhil Student
MRC MHU
NDCLS
Principal Investigators
WIMM
PhD MRCP FRCPath Adam Mead - Professor of Haematology
MRC MHU
NDCLS
Principal Investigators
WIMM
PhD Thomas Milne - Professor of Haematology
MRC MHU
NDCLS
Researchers
BSc, MSc Marlen Metzner - Next Generation Sequencing Lead
Administration
IMD
MRC MHU
Research Support
WIMM
BSc (Hons) Chris Groves - MRC MHU Laboratory Manager
MRC MHU
NDCLS
Researchers
WIMM
Verena Korber - Postdoctoral Fellow
MRC MHU
Researchers
Students
WIMM
Daniel North - Clinical Research Fellow and DPhil Student
MRC MHU
Students
WIMM
BA (Hons) Natural Sciences Abhimanyu Gowda - DPhil Student
MRC MHU
NDCLS
Researchers
PhD, Dipl-Biol. Jana Koth - Imaging Facility Manager
MRC MHU
NDCLS
Researchers
PhD Hana Mlcochova - Research Assistant in Medical Genetics
MRC MHU
NDCLS
Researchers
PhD Ruggiero Norfo - Postdoctoral researcher
MRC MHU
NDCLS
Researchers
MBChB; BSc; DPhil; MRCP; FRCPath Noemi Roy - Associate Professor of Molecular Haematology
MRC MHU
NDCLS
Researchers
BSc (Hons); PhD Caroline Scott - Research Assistant
MRC MHU
NDCLS
Researchers
PhD; BSc (Hons) Yan Zhou - Postdoctoral Researcher
MRC MHU
NDCLS
Researchers
WIMM
Yavor Bozhilov - Postdoctoral Researcher
MRC MHU
NDCLS
Students
DPhil Lance Hentges - Postdoctoral Scientist
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