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Research by Prof Andrew Wilkie and Prof Anne Goriely, published in PNAS, has identified the origins of some severe disease-causing mutations within the testicles of normal men. Particular mutations in the FGFR2 gene and a few other disease genes enable the mutated spermatogonia to produce not just sperm but extra copies of themselves, reproducing and spreading faster than the surrounding normal spermatogonia. This tumour-like growth means that over time, a greater proportion of sperm being produced carry disease-causing mutations, increasing the risk of fathering a child with a serious condition.
AVIC Symposium - 2017
Research
Thursday, 23 November 2017, 9.50am to 5pm
We would like to invite you to a one day symposium on acute vascular disease at the Richard Doll Building on Thursday 23rd November 2017. The day will consist of neuro and cardiac themed talks that span development / validation and applications in clinical research.