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Found 30396 matches for
Jackson Group: Lymphatic Trafficking Research Group
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.
Piechnik Group: Myocardial functional T1 mapping – Advanced cardiac magnetic resonance imaging techniques
We aim to further improve the clinical value of Cardiovascular Magnetic Resonance with application of advanced image analysis techniques.
de Bruijn Group: Developmental Haematopoiesis
MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine Nuffield Division of Clinical Laboratory Sciences
We study the embryonic origins of blood stem cells with the aim to inform the generation of these cells in culture, and ultimate produce clinically relevant blood stem cells for therapeutic purposes.
Higgs Group: Laboratory of Gene Regulation
MRC Weatherall Institute of Molecular Medicine Nuffield Division of Clinical Laboratory Sciences
We use state-of-the-art laboratory and computational approaches to understand how mammalian genes are switched on and off during development and differentiation and how this goes awry in human genetic diseases.
Davis Group: T-cell Biology
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Mead Group: Haematopoietic Stem Cell Biology
MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine Nuffield Division of Clinical Laboratory Sciences
The Haematopoietic Stem Cell Biology (HSCB) Laboratory is focused on understanding how the normal haematopoietic stem/progenitor hierarchy is disrupted during the development of myeloid malignancies. Our overarching aim is to improve the management of myeloproliferative neoplasms and related conditions through better monitoring and therapeutic targeting of malignant stem cell populations.
Neubauer Group: Oxford Centre for Clinical Magnetic Resonance Research
Division of Cardiovascular Medicine Oxford Centre for Clinical Magnetic Resonance Research
OCMR uses sophisticated cardiac MR imaging and spectroscopy methods to phenotype cardiovascular disease – in small-scale proof-of-principle studies, large-scale multicentre clinical trials and ultra-large scale population imaging programmes. As well as running their own research programmes, OCMR serves as a collaboration partner to any group wanting to strengthen their clinical research with state of the art non-invasive phenotyping tools.
Vyas Group: Biology and Treatment of Human Myeloid Cancers
MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine Nuffield Division of Clinical Laboratory Sciences
We aim to understand the fundamental biological processes underlying normal and malignant haematopoiesis and translate this to improve patient outcomes through new rational therapies.
Redwood Group: Cardiac Contractility
Division of Cardiovascular Medicine
Defining important functional paradigms that lead to inherited cardiomyopathies, in search of novel treatments.
Kerr and Pezzella Group: Colorectal Clinical and Pathology Group
Nuffield Division of Clinical Laboratory Sciences
We lead colorectal cancer clinical trials, and study the basic biology of non-angiogenic and angiogenic tumours and mechanisms of vascular co-option.
Hughes Group: Genome Biology
MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine Nuffield Division of Clinical Laboratory Sciences
Using genomics, computational and synthetic biology approaches to understand how genes are regulated in health and disease.
Gill and Hyde Group: Gene Medicine Group
Nuffield Division of Clinical Laboratory Sciences
We are developing gene therapy for lung conditions, including the genetic disease Cystic Fibrosis (CF) and neonatal lung conditions such as surfactant protein B (SPB) deficiency. We are also evaluating whether the lung can be used as a ‘protein factory’ to make therapeutic proteins such as antibodies.
Ferreira Group: Quantitative cardiac magnetic resonance myocardial tissue characterisation
Division of Cardiovascular Medicine Oxford Centre for Clinical Magnetic Resonance Research
We have expertise in the study of heart disease using cardiovascular magnetic resonance (CMR), particularly quantitative techniques such as myocardial T1-mapping.
Adler Group: Diabetes Trials Unit
Oxford Centre for Diabetes, Endocrinology and Metabolism
The Diabetes Trials Unit (DTU) is a clinical trials unit specialising in performing local, national and multinational clinical trials related to treating and managing diabetes and other cardiometabolic and related conditions.
Betts Group: Cardiac Rhythm Management
Division of Cardiovascular Medicine
The CRM group’s principal research interests are the treatment of abnormal heart rhythms and the resynchronisation of abnormal electrical conduction in heart failure patients. There is a particular focus on the use of novel and emerging technologies.
Buchan Group: Laboratory of Cerebral Ischemia
Investigative Medicine Division
The Laboratory of Cerebral Ischemia is a pre-clinical research group aiming to discover both the mechanisms which underlie cell death in stroke and to develop novel strategies to reduce this.
Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology
Division of Cardiovascular Medicine
Channon Group: Cardiovascular functional genomics and redox signalling
Division of Cardiovascular Medicine
We work to understand how early changes in cells of the cardiovascular system, such as endothelial cells and leukocytes, are related to cardiovascular disease, with a particular focus on redox biology.
Watkins Group: Inherited Heart Muscle Disease Group
Division of Cardiovascular Medicine
Using human genetics and functional genomics to understand inherited heart disease
Inherited Heart Disease Service
Division of Cardiovascular Medicine
We make about 1600 patient contacts a year with those who have, or are at risk of having, an Inherited Cardiac Condition (eg cardiomyopathies and inherited arrhythmias) across all age ranges. We provide cardiology screening (ECG, Echocardiography) and clinical genetics during an initial single clinic visit, and provide telephone and e-mail support throughout the working week. We have made internationally recognised contributions in this area, in particular the use of cardiac MRI in diagnosis, and understanding of the underlying genetic basis of Inherited Cardiac Conditions.