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Nicknamed ‘Why?’ during his years as a student nurse, Tony O’Malley is always asking questions. His quest for explanations is a trait that’s come in handy time and time again in his role as a patient advocate. ony recently won the 2015 Supporter of the Year Gold Award in the Oxford University Hospitals NHS Foundation Trust, Annual Staff Recognition Awards, a testament to his tireless campaigning to improve patient safety and patient engagement in diabetes care. I caught up with him to learn more about what got him involved in patient advocacy and how we can all work together to improve clinical care.
Royston Group - AI-based Analysis of the Bone Marrow; Integrating Spatial Transcriptomics & Multiplexed Imaging To Improve the Assessment of Blood Cancer (Funding Available)
The diagnosis of blood cancer requires integration of clinical, pathological, immunophenotypic and genetic / molecular findings. Accurate and consistent interpretation of bone marrow trephines (BMT) is particularly important for distinguishing between important blood cancer subtypes. Such distinction guides patient management and informs risk stratification. In response, our group have developed pioneering artificial intelligence (AI) approaches to accurately capture important tissue features of the bone marrow in blood cancer. This includes the development of automated and quantitative approaches to detect cellular and stromal changes present on routinely prepared diagnostic samples. We are now developing strategies to combine these approaches with newly developed advanced spatial transcriptomic and IHC / IF multiplexing strategies for patient-derived bone marrow biopsies.