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The American Society of Hematology (ASH) and the European Hematology Association (EHA) have announced the names of 20 early-career hematologists who will participate in the joint 2017 Translational Research Training in Hematology (TRTH) program. These include Dr Alice Giustacchini (WIMM-NDCLS, Mead/Jacobsen Group) and Dr Lynn Quek (WIMM-NDCLS, Vyas Group). Congratulations to Alice and Lynn for being invited to take part in this prestigious scheme.
Royston Group - AI-based Analysis of the Bone Marrow; Integrating Spatial Transcriptomics & Multiplexed Imaging To Improve the Assessment of Blood Cancer (Funding Available)
The diagnosis of blood cancer requires integration of clinical, pathological, immunophenotypic and genetic / molecular findings. Accurate and consistent interpretation of bone marrow trephines (BMT) is particularly important for distinguishing between important blood cancer subtypes. Such distinction guides patient management and informs risk stratification. In response, our group have developed pioneering artificial intelligence (AI) approaches to accurately capture important tissue features of the bone marrow in blood cancer. This includes the development of automated and quantitative approaches to detect cellular and stromal changes present on routinely prepared diagnostic samples. We are now developing strategies to combine these approaches with newly developed advanced spatial transcriptomic and IHC / IF multiplexing strategies for patient-derived bone marrow biopsies.