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Congratulations to Prof Alastair Buchan (IMD) and Prof Rury Holman (OCDEM) who have both been re-appointed as NIHR Senior Investigators. Senior Investigators are the NIHR’s pre-eminent researchers and represent the country’s most outstanding leaders of clinical and applied health and social care research.

Logo of the National Institute for Health Research (NIHR).

Toepfer Group: Elucidating the role of disease modifying gene variants in inherited cardiomyopathies using induced pluripotent stem cell derived cardiomyocytes and CRISPR/Cas-9

Raman Group: Pioneering Precision Medicine in Hypertrophic Cardiomyopathy: Advanced Imaging, Machine Learning, and Translational Research for Early Detection and Targeted Therapies

Ormondroyd Group: Development of genetic therapies for cardiomyopathy: creating an evidence base for ethical and clinical implementation

MRC Enterprise Studentship (iCASE): An exploration of the Heart - Liver axis: using MRI to understand how and why measurements taken in the liver relate to adverse cardiovascular outcomes

MRC Enterprise Studentship (iCASE): Developing hardware and software to improve Magnetic Resonance Neuroimaging

Psaila Group: How does altered mechanobiology of the cancer microenvironment perturb cell cycle controls and cause genome instability?

Pavlides Group: Non-invasive tests for the prediction of clinical outcomes in people with metabolic dysfunction associated steatotic liver disease

Cai Group: Metabolic and inflammatory crosstalk in the tumour microenvironment

Douglas Group: Functional coronary artery disease genetics - defining the function of new causal atherosclerosis genes

Higgs Group: Understanding the principles of gene expression in health and disease.

Antoniades Group: Cross-talk between adipose tissue and the cardiovascular system in humans: Using Artificial Intelligence to design precision Imaging diagnostics and discover novel therapeutic targets

Hodson Group: Human liver fat metabolism and metabolic disease

Watkins Group: Various relating to inherited heart muscle disease

Tzima Group: Can we harness novel therapeutics to inhibit inflammation and cardiovascular disease?

Tyler Group: Development and Application of Hyperpolarized Magnetic Resonance Imaging in the Study of the Diseased Heart

Reader Group: How do protein making factories prevent cardiovascular disease?

Nerlov Group: Single Cell Biology and Genetics of Hematopoietic Stem- and Progenitor cells in Blood Cancer and Ageing

Nasteska Group: Islet protein synthesis dynamics in health and type 2 diabetes

Mead Group: Gene-Environment Initiated Disease Progression in Myeloproliferative Neoplasms

Lewis Group: Imaging mitochondrial trafficking and dynamics in the failing heart

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