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Lewis Group: Spatial Cardiology
From molecules to medicines for failing hearts.
Khan Lab: Engineering Human Pre-Clinical Models
We engineer complex human models to dissect how cell-to-cell and cross-tissue interactions shape health and disease. By recreating specialised microenvironments – from bone marrow to cardiac tissue – we study how ageing and disease can drive changes in these niches. Our goal is to ultimately use these approaches as translational tools to identify new therapies and validate them in relevant, human pre-clinical platforms.
The Oxford Stone Group
Throughout history, stones have formed in the urinary tract (kidney and bladder). We are learning more about kidney stone disease and how best to prevent, diagnose and treat this condition.
Sharma Group: Mechanistic T Cell Genomics
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
Our research team is focused on uncovering the mechanisms that govern T cell signaling, with the goal of precisely engineering immune cells for immunotherapies.
Curry Group: Endothelial regulation of haemostasis in health and disease
We study the mechanisms by which vascular endothelial cells regulate haemostasis in health and in acquired bleeding disorders, namely trauma-induced coagulopathy, to better understand disease pathogenesis and identify novel therapeutic targets.
Zimmermann Group: Iron Nutrition - Stable Isotopes and Therapeutics
The overarching goal of our research is to improve iron nutrition and reduce the burden of anaemia among women and children. To achieve this, we employ innovative stable iron isotope techniques to precisely trace iron absorption, distribution, and utilization in the human body. These approaches inform the design and development of novel iron therapeutics. By integrating mechanistic understanding with therapeutic innovation, our work aims to deliver iron interventions with enhanced safety and efficacy.
Lapidaire Group: Brain Health Vascular Imaging
Our group aims to make early diagnosis and continuous check-ups for (vascular) diseases accurate, affordable, and accessible for everyone. We focus on women’s vascular health and global health and aim to better understand the impact of hypertensive disorders of pregnancy on the brain.
Valkovič Group: Body MRS Group
Pushing the Limits of Multi-nuclear Magnetic Resonance Spectroscopy of the Heart, Liver and Muscle
Zhang Group: Artificial Intelligence in Cardiovascular Imaging
We work with clinicians and MR scientists on a day-to-day basis to develop novel AI machine-learning approaches for cardiovascular imaging.
Akbar Group: Extracellular Vesicles in Cardiovascular, Inflammatory and Metabolic Disease
The Akbar Lab is interested in defining the therapeutic and diagnostic potential of extracellular vesicles for immunomodulation and precision medicine in cardiovascular, metabolic, and inflammatory diseases.