Search results
Found 13 matches for
Sharma Group: Mechanistic T Cell Genomics
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
Our research team is focused on uncovering the mechanisms that govern T cell signaling, with the goal of precisely engineering immune cells for immunotherapies.
Zimmermann Group: Iron Nutrition - Stable Isotopes and Therapeutics
The overarching goal of our research is to improve iron nutrition and reduce the burden of anaemia among women and children. To achieve this, we employ innovative stable iron isotope techniques to precisely trace iron absorption, distribution, and utilization in the human body. These approaches inform the design and development of novel iron therapeutics. By integrating mechanistic understanding with therapeutic innovation, our work aims to deliver iron interventions with enhanced safety and efficacy.
Koohy Group: Machine Learning and Integrative Approaches in Immunology
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.
Simmons Group: Intestinal Immunity in Health and Disease
We define how the immune system functions in the intestine to promote health. We uncover the immune pathogenesis of intestinal diseases such as inflammatory bowel disease to develop better ways to treat these disorders.
Jackson Group: Lymphatic Trafficking Research Group
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.
Davis Group: T-cell Biology
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Skin Immunology Group
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
The aim of the group is to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. We have a particular focus on T cells which recognise inflammatory lipids presented by CD1a. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Drakesmith Group: Iron and Immunity
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.