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Search results (10)

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Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.

Ren H. et al, (2026), Blood, 147, 180 - 196

Bi-specific CAR-iNKT cell immunotherapy for high-risk KMT2A-rearranged leukemia outperforms CAR-T in an NKG2D-dependent manner and eradicates leptomeningeal disease

Ren H. et al, (2025)

Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia.

Cogswell TJ. et al, (2024), RSC Med Chem, 15, 3495 - 3506

The Fetal Specific Gene LIN288 Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Ling RE. et al, (2024), BLOOD, 144, 199 - 200

The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.

Muskens IS. et al, (2021), Nat Commun, 12

H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells.

Godfrey L. et al, (2021), Leukemia, 35, 90 - 106

The Origin of B-cells: Human Fetal B Cell Development and Implications for the Pathogenesis of Childhood Acute Lymphoblastic Leukemia.

Jackson TR. et al, (2021), Front Immunol, 12

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua P. et al, (2020), Blood, 136, 2410 - 2415

novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL

Rice S. et al, (2020)

Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen.

Owens GL. et al, (2017), Cancer Med, 6, 408 - 415