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Search results (36)

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CIP2A mediates mitotic recruitment of SLX4/MUS81/XPF to resolve replication stress-induced DNA lesions.

de Haan L. et al, (2025), Nat Commun, 17

The ERCC6L2-MRI-KU complex coordinates NHEJ at staggered DNA double-strand breaks

Reichl PI. et al, (2025)

Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice.

King A. et al, (2025), Nat Struct Mol Biol, 32, 86 - 97

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.

Tsukada K. et al, (2024), Mol Cell, 84, 640 - 658.e10

Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice.

King A. et al, (2023)

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.

Rodriguez-Meira A. et al, (2023), Nat Genet, 55, 1531 - 1541

53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis.

Mirman Z. et al, (2022), Nat Cell Biol, 24, 51 - 61

BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.

Becker JR. et al, (2021), Nature, 596, 433 - 437

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Hewitt G. et al, (2021), Mol Cell, 81, 767 - 783.e11

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

Yeow ZY. et al, (2020), Nature, 585, 447 - 452

Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.

Francica P. et al, (2020), Cell Rep, 32

BARD1 links histone H2A Lysine-15 ubiquitination to initiation of BRCA1-dependent homologous recombination

Becker J. et al, (2020)

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

Nakamura K. et al, (2019), Nat Cell Biol, 21, 311 - 318

n essential role for the Zn2+ transporter ZIP7 in B cell development.

Anzilotti C. et al, (2019), Nat Immunol, 20, 350 - 361

H4K20meO recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

Nakamura K. et al, (2019), NATURE CELL BIOLOGY, 21, 311 - +

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