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Search results (75)

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MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemia.

Lau I-J. et al, (2026), Blood

Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in pneumonia-associated sepsis.

Zhang P. et al, (2026), Nat Commun, 17

Menin maintains enhancer-promoter interactions in a leukemia-specific manner

Sharlandjieva V. et al, (2026)

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions.

Li H. et al, (2025), Cell, 188, 7175 - 7193.e19

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.

Smith AL. et al, (2025), Blood, 146, 2073 - 2087

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.

Brierley CK. et al, (2025), Nat Genet, 57, 1478 - 1492

Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.

Preston AE. et al, (2025), Nat Commun, 16

The state-of-the-art of N-of-1 therapies and the IRDiRC N-of-1 development roadmap.

Jonker AH. et al, (2025), Nat Rev Drug Discov, 24, 40 - 56

Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in sepsis, modulating disease

Zhang P. et al, (2025)

Towards a directed evolution approach to improve lentiviral vector targeting

Cerezuela MMP. et al, (2025), HUMAN GENE THERAPY, 36, E365 - E365

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.

Rahman S. et al, (2024), Blood, 144, 2319 - 2326

Single-cell technologies meet Hi-C.

Hughes JR. and Davies JOJ., (2024), Nat Genet, 56, 1542 - 1543

Pioneer activity distinguishes activating from non-activating SOX2 binding sites.

Maresca M. et al, (2023), EMBO J, 42

Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.

Downes DJ. et al, (2023), Nat Protoc, 18

Ancient genomic linkage couples metabolism with erythroid development.

Preston AE. et al, (2023), bioRxiv

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