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Search results (15)

« Back to Publications

FACT safeguards promoter topology by maintaining nucleosomes and restricting chromatin factor spreading

Dopico-Fernandez AM. et al, (2026)

Menin maintains enhancer-promoter interactions in a leukemia-specific manner

Sharlandjieva V. et al, (2026)

A genome-wide screen identifies Runx2 as a novel regulator of hematopoietic stem cell expansion and T-cell commitment.

Meaker GA. et al, (2025), Blood, 146, 3188 - 3200

Menin inhibitor DS-1594b drives differentiation and induces synergistic lethality in combination with venetoclax in acute myeloid leukemia cells with rearranged mixed-lineage leukemia and mutated nucleophosmin-1.

Ciaurro V. et al, (2025), Haematologica

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.

Smith AL. et al, (2025), Blood, 146, 2073 - 2087

TRANSCRIPTION ELONGATION AND ABERRANT ENHANCER ACTIVATION IN LEUKEMIA

Milne T. et al, (2025), EXPERIMENTAL HEMATOLOGY, 151

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression between patients

Smith A. et al, (2024)

The fetal specific geneLIN28Bis essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia

Ling R. et al, (2024)

The Fetal Specific Gene LIN288 Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Ling RE. et al, (2024), BLOOD, 144, 199 - 200

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Smith AL. et al, (2024), BLOOD, 144, 201 - 202

Endothelial sensing of AHR ligands regulates intestinal homeostasis.

Wiggins BG. et al, (2023), Nature, 621, 821 - 829

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.

Crump NT. et al, (2023), Nat Commun, 14

Endothelial sensing of AHR ligands regulates intestinal homeostasis

Wiggins BG. et al, (2023)

A High-Throughput Cell Culture Model of Idiopathic Pulmonary Fibrosis (IPF) for Gene Therapy Applications

Cerezuela MP. et al, (2022), MOLECULAR THERAPY, 30, 292 - 292

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.

de Jesus DS. et al, (2021), Mol Metab, 53