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Search results (24)

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A functional overlap between actively transcribed genes and chromatin insulator elements.

Cornell LJ. et al, (2026), EMBO J

Facilitators may represent a new class of regulatory elements.

Kassouf M. et al, (2026), Curr Opin Genet Dev, 97

Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.

Preston AE. et al, (2025), Nat Commun, 16

Author Correction: The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

The characteristics of CTCF binding sequences contribute to enhancer blocking activity.

Tsang FH. et al, (2024), Nucleic Acids Res, 52, 10180 - 10193

Developing a pill to treat sickle cell disease.

Higgs D. and Kassouf M., (2024), Science, 385, 27 - 28

Super-enhancers include classical enhancers and facilitators to fully activate gene expression.

Blayney JW. et al, (2023), Cell, 186, 5826 - 5839.e18

Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α-globin locus.

Kassouf M. et al, (2023), Bioessays, 45

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

Tsang F. et al, (2023)

Active regulatory elements recruit cohesin to establish cell-specific chromatin domains

Georgiades E. et al, (2023)

Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation

Stolper R. et al, (2023)

Scalable in vitro production of defined mouse erythroblasts.

Francis HS. et al, (2022), PLoS One, 17

Reactivation of a developmentally silenced embryonic globin gene.

King AJ. et al, (2021), Nat Commun, 12

The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization.

Oudelaar AM. et al, (2021), Curr Opin Genet Dev, 67, 18 - 24

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