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Search results (67)

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DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.

van der Sluijs RV. et al, (2025), Nucleic Acids Res, 53

Embracing cancer complexity: Hallmarks of systemic disease.

Swanton C. et al, (2024), Cell, 187, 1589 - 1616

ldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism.

John T. et al, (2024), Chem Sci, 15, 2509 - 2517

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.

Pham VN. et al, (2023), Science, 382

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.

Wang M. et al, (2023), Mol Cell, 83, 2417 - 2433.e7

istone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production.

Wit N. et al, (2023), Sci Adv, 9

Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links.

Morton SB. et al, (2023), J Am Chem Soc, 145, 953 - 959

Genotoxic aldehydes in the hematopoietic system.

Wang M. et al, (2022), Blood, 139, 2119 - 2129

ldehyde-driven transcriptional stress triggers an anorexic DNA damage response.

Mulderrig L. et al, (2021), Nature, 600, 158 - 163

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.

Dingler FA. et al, (2020), Mol Cell, 80, 996 - 1012.e9

mino acid dependent formaldehyde metabolism in mammals.

Pietzke M. et al, (2020), Commun Chem, 3

FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.

Alcón P. et al, (2020), Nat Struct Mol Biol, 27, 240 - 248

lcohol-derived DNA crosslinks are repaired by two distinct mechanisms.

Hodskinson MR. et al, (2020), Nature, 579, 603 - 608

Structure of the Fanconi anaemia monoubiquitin ligase complex.

Shakeel S. et al, (2019), Nature, 575, 234 - 237

structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.

Bauer MR. et al, (2019), Future Med Chem, 11, 2491 - 2504

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