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Search results (191)

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FACT safeguards promoter topology by maintaining nucleosomes and restricting chromatin factor spreading

Dopico-Fernandez AM. et al, (2026)

Correction to "DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement".

Kashyap D. et al, (2026), JACS Au, 6, 653 - 655

Menin maintains enhancer-promoter interactions in a leukemia-specific manner

Sharlandjieva V. et al, (2026)

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.

Ren H. et al, (2026), Blood, 147, 180 - 196

genome-wide screen identifies Runx2 as a novel regulator of hematopoietic stem cell expansion and T-cell commitment.

Meaker GA. et al, (2025), Blood, 146, 3188 - 3200

Zone Equalisation Normalisation For Improved Alignment of Epigenetic Signal

Wilson T. et al, (2025)

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions.

Li H. et al, (2025), Cell, 188, 7175 - 7193.e19

Small proteins with a big job: An EMBOW-derived microprotein targets WDR5-MLL1 and suppresses transcription in leukemia.

Baillie HL. and Milne TA., (2025), Cell Chem Biol, 32, 1305 - 1307

Menin inhibitor DS-1594b drives differentiation and induces synergistic lethality in combination with venetoclax in acute myeloid leukemia cells with rearranged mixed-lineage leukemia and mutated nucleophosmin-1.

Ciaurro V. et al, (2025), Haematologica

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.

Smith AL. et al, (2025), Blood, 146, 2073 - 2087

PROM1/CD133 marks a proliferative stem cell-like population of blasts in KMT2A rearranged infant ALL.

Cross JW. et al, (2025), Blood Adv, 9, 4607 - 4613

DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement.

Kashyap D. et al, (2025), JACS Au, 5, 3799 - 3807

Harnessing BET-Bromodomain Assisted Nuclear Import for Targeted Subcellular Localization and Enhanced Efficacy of Antisense Oligonucleotides.

Kashyap D. et al, (2025), J Am Chem Soc, 147, 29478 - 29488

Engineering antisense oligonucleotides for targeted mRNA degradation through lysosomal trafficking.

Kashyap D. et al, (2025), Chem Sci, 16, 13096 - 13105

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Teh MR. et al, (2025), Nat Commun, 16

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